Anticonvulsant hypersensitivity syndrome (AHS) is a rare, severe drug hypersensitivity reaction included in the drug-related rash with eosinophilia and systemic symptoms syndrome (DRESS), in which a transient state of immune suppression and reactivation of latent virus infections have been observed. We describe 5 patients who developed neosensitization to different drugs taken during a previous...

The purpose of this research was to provide a critical review of key research areas within the social psychology of dress. The review addresses published research in two broad areas: (1) dress as a stimulus and its influence on (a) attributions by others, attributions about self, and on one's behavior and (2) relationships between dress, the body, and the self. We identify theoretical approache...

Clothes are central to how we perform our identities. In this article we show how these processes continue to operate in the lives of people with dementia, exploring the ways in which dress offers a means of maintaining continuity of self at a material, embodied level. The article thus contributes to the wider cultural turn in ageing studies, showing how material objects are significant in mean...

BACKGROUND Drug reaction with eosinophilia and systemic symptoms (DRESS) is a severe hypersensitivity drug reaction involving the skin and multiple internal organ systems. The symptoms typically present with fever and skin rash, and rapidly progress to multiple organ failures. Vancomycin is a rare drug to cause DRESS syndrome with 23 cases reported to date. CASE PRESENTATION We described a ca...

Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome reflects a serious hypersensitivity reaction to drugs, characterized by skin rash, fever, lymph node enlargement, and internal organ involvement. So far, numerous drugs such as sulfonamides, phenobarbital, sulfasalazine, carbamazepine, and phenytoin have been reported to cause the DRESS syndrome. We report a case in a 29-yr-old ...

'The dress' is a peculiar photograph: by themselves the dress' pixels are brown and blue, colors associated with natural illuminants, but popular accounts (#TheDress) suggest the dress appears either white/gold or blue/black. Could the purported categorical perception arise because the original social-media question was an alternative-forced-choice? In a free-response survey (N = 1401), we foun...

T-cell receptor (TCR)-mediated cross-recognition is a major mechanism in the pathogenesis of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. However, the characteristics of the TCR repertoire and the clinical significance of repertoire reformation throughout the course of DRESS are unknown. Here, we isolated CD4(+) and CD8(+) T-cells from peripheral blood of 8 DRESS pati...

Drug reaction with eosinophilia and systemic symptoms (DRESS) or drug-induced hypersensitivity syndrome (DIHS) involves a unique and severe adverse drug reaction. Patients present with fever, rash, lymphadenopathy, hematological abnormalities, systemic illness, and may suffer from prolonged courses. Although the precise pathogenesis of DRESS/DIHS is not fully understood, it is widely considered...

Andrea Mazzolini, Marco Gherardi, 3 Michele Caselle, Marco Cosentino Lagomarsino, 3, 4 and Matteo Osella∗1 Physics Department and INFN, University of Turin, via P. Giuria 1, 10125 Turin, Italy Sorbonne Universités, UPMC Univ Paris 06, UMR 7238, Computational and Quantitative Biology, 15 rue de l’École de Médecine Paris, France CNRS, UMR 7238, Paris, France FIRC Institute of Molecular Oncology (...

DRESS syndrome is an idiosyncratic reaction to drugs, which can occur in both adults and children. To date there is no agreed upon criteria for its diagnosis; there is even less consensus on its management. We report the case of a 14- year-old boy with carbamazepine induced DRESS syndrome, predominantly involving the liver. He responded rapidly to high dose pulsed intravenous corticosteroids.