This study was performed to investigate some clinical parameters of febrile seizures (FSs) in patients with epilepsy, testing any possible correlation between those parameters and the type of subsequent epilepsy. One hundred and nine patients with epilepsy having a history of FSs were evaluated for age at onset of FSs, interval between first FS and first afebrile seizure, recurrence rate, type ...

Epilepsy is a group of disorder characterized by two or more unprovoked seizures. The estimated average prevalence of epilepsy in US is 6.8 per 1000, Europe is 5.5 per 1000, and Asia is 1.5 to 14 per 1000 people respectively. [1] Epilepsy is classified based on the source of seizure into partial and generalized seizures. [1] About 2/3rd of newly diagnosed epilepsies are partial or secondarily g...

Epilepsy is a disease with serious consequences for patients and society. In many cases seizures are sufficiently disabling to justify surgical evaluation. In this context, Magnetic Resonance Imaging (MRI) is one of the most valuable tools for the preoperative localization of epileptogenic foci. Because these lesions show a large variety of presentations (including subtle imaging characteristic...

INTRODUCTION Hormonal fluctuation is responsible for worsening of epileptic seizures during the menstrual cycle. OBJECTIVE To identify irregularities in the menstrual cycles of women with mesial temporal lobe epilepsy (MTLE) and extratemporal focal epilepsy (ETFE) and correlate the frequency of seizures during the menstrual cycles. METHOD We evaluated prospectively women in the menacme with...

Considerable attention has been paid in recent times to cellular and synaptic mechanisms involved in epileptogenesis. A number of in vivo and in vitro animal models are now available to study basic mechanisms of epileptogenesis and to select and evaluate antiepileptic compounds which could be potentially effective in human epilepsy. Although this approach has been useful for practical purposes,...

BACKGROUND We evaluated the diagnostic value of Electroencephalography (EEG), video-EEG monitoring (VEM) and Magnetic resonance imaging (MRI) of the brain with epilepsy protocol in patients with complex partial epilepsy. METHODS Forty-two consecutive patients underwent complete neurological examination, EEG, and MRI with a modified epilepsy protocol. A subset of these patients (n = 29) also u...

conclusions administration of aeds in general and levetiracetam in particular should be based on attention to pharmacokinetic behavior in terms of monotherapy or polypharmacy. case presentation two cases were studied, one patient was a 32-year-old male and the other was a 14-year-old female. the key words relevant to search topics were surveyed using pubmed (united states national library of me...

Some patients with epilepsy not controlled by medication will benefit from surgical removal of the seizure focus in the brain, if the seizure focus can be identified. The seizure focus has to be localized in one hemisphere only. This is referred to as refractory complex partial epilepsy. The problem is that identification of the seizure focus is not easily accomplished. One way to identify the ...

More than 20 years ago, complex partial epilepsy of occipital-temporal origin was suggested as having been the "nervous disease" of Gustave Flaubert, one of the most famous French novelists. The aim of the present work, therefore, was to reevaluate the diagnosis of Flaubert's "nervous disease" in the light of reemerged biographic information and letters, as well as the numerous scientific advan...

PURPOSE To determine the safety, in our practice, of allowing patient preference to influence the timing of antiepileptic drug (AED) reduction, once they became seizure-free after anterior temporal lobectomy (ATL). METHODS Thirty patients underwent anterior temporal lobectomy for medically intractable complex partial epilepsy at Loma Linda University Medical Center between December 1st 1991 a...