PURPOSE To determine whether the proton spectra from patients with clinically diagnosed Parkinson disease differ from the spectra of age-matched healthy subjects with respect to the major cerebral metabolite resonances as well as lactate. METHODS Fourteen patients with Parkinson disease (38 to 81 years of age) and 13 healthy control subjects (37 to 81 years of age) were studied using image-gu...

INTRODUCTION This epidemiological survey estimates the hospitalization burden related to Parkinson´s Disease in Spain. METHODS This observational retrospective survey was performed by reviewing data from the National Surveillance System for Hospital Data, which includes more than 98% of Spanish hospitals. All hospitalizations of patients with Parkinson´s disease that were reported from 1997-2...

OBJECTIVE To investigate whether serum vitamin D level predicts the risk of Parkinson disease. DESIGN Cohort study. SETTING The study was based on the Mini-Finland Health Survey, which was conducted from 1978 to 1980, with Parkinson disease occurrence follow-up through the end of 2007. During the 29-year follow-up period, 50 incident Parkinson disease cases occurred. Serum 25-hydroxyvitamin...

background: patients with parkinson's disease (pd) have different cognitive impairments.the goal of this study is the analysis of these changes in the mentioned patients.a cross-sectional study was performed on 87 patients with pd. patients were given a questionnaire to gather data about their medical and living statuses. to assess cognitive assessment, scopa-cog (scales for outcome in parkinso...

objectives: one of the problems in the process of assessment and evaluation, especially of clinical training in rehabilitation disciplines, is the lack of an instrument with objective criteria for evaluation. considering the effects of appropriate evaluation on quality assurance of clinical training, the aim of the present study was to design a valid and reliable tool for general evaluation of ...

Mutations in GBA, the gene encoding glucocerebrosidase, the enzyme deficient in Gaucher disease, are common risk factors for Parkinson disease, as patients with Parkinson disease are over five times more likely to carry GBA mutations than healthy controls. Patients with GBA mutations generally have an earlier onset of Parkinson disease and more cognitive impairment than those without GBA mutati...

Committee of the European Academy of Neurology in Brussels, Belgien. He is also a member of the high level advisory board for the European Ministry for Research and Development " Scientific Panel for Health (SPH) ". He has received many prestigious awards during his career, including the " carrier award for basal ganglia disorders " On the International Conference: Clinical Update Sleep 2016, w...

BACKGROUND AND PURPOSE The pathology of Parkinson disease leads to morphological brain volume changes. So far, the progressive gray matter volume change across time specific to patients with Parkinson disease compared controls remains unclear. Our aim was to investigate the pattern of gray matter changes in patients with Parkinson disease and to explore the progressive gray matter volume change...

Segundo a portaria n° 228, de 10 maio 2010 do Ministério da Saúde, doença Parkinson (DP), antes descrita por James em 1817, é uma das doenças neurológicas mais comuns e intrigantes atualidade. A patologia caracterizada quatro sinais clínicos essenciais: Tremor repouso, rigidez, bradicinesia instabilidade postural. O presente estudo avaliou importância atuação fisioterapia na Parkinson, buscando...