OBJECTIVE Since March 1992, intravenous nalbuphine hydrochloride has been used prehospital by paramedics in the Plymouth area. This study assesses the impact of this intervention. METHODS A prospective study of the parenteral analgesic requirements of 1000 consecutive patients arriving by ambulance at the accident and emergency (A&E) department of a large district general hospital. Where pare...

OBJECTIVE To compare the efficacy and cost of enteral and parenteral feeding after total gastrectomy. DESIGN Prospective randomised open study. SETTING University hospital, Finland. SUBJECTS 29 patients undergoing curative total gastrectomy for gastric cancer. INTERVENTIONS 13 patients were given early enteral feeding by nasojejunal tube and 16 patients parenteral nutrition by central v...

The role of enteral or parenteral long-chain triacylglycerol (LCT) in the complex process of intestinal adaptation is poorly defined and may involve alterations in eicosanoid synthesis. Our objective was to determine whether provision of parenteral LCT stimulates eicosanoid synthesis and resection-induced intestinal adaptation. We assessed small bowel structural adaptation, the fatty acid profi...

Patients undergoing pancreaticoduodenectomy (PD) often require postoperative artificial nutrition. This trial was undertaken to evaluate whether the route of administration and the composition of the postoperative nutritional support could affect the immunometabolic response and outcome. A prospective, randomized trial was carried out in 212 subjects who underwent PD. Patients were randomized t...

The role of enteral or parenteral long-chain triacylglycerol (LCT) in the complex process of intestinal adaptation is poorly defined and may involve alterations in eicosanoid synthesis. Our objective was to determine whether provision of parenteral LCT stimulates eicosanoid synthesis and resection-induced intestinal adaptation. We assessed small bowel structural adaptation, the fatty acid profi...

INTRODUCTION The potential benefit of parenteral glutamine (GLN) supplementation has been one of the most commonly studied nutritional interventions in the critical care setting. The aim of this systematic review was to incorporate recent trials of traditional parenteral GLN supplementation in critical illness with previously existing data. METHODS All randomized controlled trials of parenter...

Objective: Zataria multiflora has been reported to have several medicinal properties including antioxidant, antibacterial, antispasmodic, and expectorant activities. This study aimed to investigate the effect of Z. multiflora hydro-alcoholic extract (ZMHE) on peptic ulcer caused by indomethacin in rats. Materials and Methods: ZMHE was prepared by maceration,  condensed by rotary evaporator and ...

Total Parenteral Beslenme (TPN) oral veya enteral yoldan beslenemeyen hastalara uygulanmaktadır. beslenmenin en yaygın kullanıldığı bebek grubu prematüre bebeklerdir. bebeklerde ilk başarılı uygulamaları 1960’lı yıllarda yapılmıştır. Prematüre parenteral beslenme gereksinim duyulan karbonhidrat, protein, yağ, vitamin ve mineralleri karşılamalıdır. Bu grup doğumdan sonra glikoz, 12 saat içinde a...

Objective To conduct an economic analysis of enteral and parenteral diet costs according to the type of disease and outcome (survivors versus deaths). Methods It is a cross-sectional, observational, retrospective study with a qualitative and quantitative design, based on analysis of hospital accounts from a healthcare insurance provider in the Southern region of Brazil. Results We analyzed ...