نتایج جستجو برای: parapoxvirus

تعداد نتایج: 173  

Journal: :Clinical Diagnostic Laboratory Immunology 1999

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Journal: :Frontiers in Microbiology 2019

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2014
Alistair C. Darby Colin J. McInnes Karina Hansen Kjær Ann R. Wood Margaret Hughes Pia Møller Martensen Alan D. Radford Neil Hall Julian Chantrey

Squirrelpox virus (SQPV) shows little evidence for morbidity or mortality in North American grey squirrels (Sciurus carolinensis), in which the virus is endemic. However, more recently the virus has emerged to cause epidemics with high mortality in Eurasian red squirrels (S. vulgaris) in Great Britain, which are now threatened. Here we report the genome sequence of SQPV. Comparison with other P...

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Journal: :Journal of Veterinary Diagnostic Investigation 2013

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2003

The website is maintained by a research unit based at the University of Liverpool that aims to provide information on the ecology and management of invasive species in the United Kingdom. The site provides species descriptions, life history details, range information as well as discussing the impacts and potential control measures of eastern grey squirrels. Eastern grey squirrels were introduce...

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2010
Henning Lauterbach Barbara Bathke Stefanie Gilles Claudia Traidl-Hoffmann Christian A. Luber György Fejer Marina A. Freudenberg Gayle M. Davey David Vremec Axel Kallies Li Wu Ken Shortman Paul Chaplin Mark Suter Meredith O’Keeffe Hubertus Hochrein

Polyinosinic:polycytidylic acid (poly IC), a double-stranded RNA, is an effective adjuvant in vivo. IFN-λs (also termed IL-28/29) are potent immunomodulatory and antiviral cytokines. We demonstrate that poly IC injection in vivo induces large amounts of IFN-λ, which depended on hematopoietic cells and the presence of TLR3 (Toll-like receptor 3), IRF3 (IFN regulatory factor 3), IRF7, IFN-I recep...

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2011
Zhangyong Ning Yongzheng Peng Wenbo Hao Chaohui Duan Daniel L Rock Shuhong Luo

BACKGROUND Reporter genes are often used as a selectable marker for generation of recombinant viruses in order to investigate the mechanism of pathogenesis and to obtain candidate vaccine viruses. Routine selection of the recombinant parapoxvirus is time-consuming and labor intensive. Therefore, developing a novel method for selection is critical. RESULTS In this study, we developed a rapid m...

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Journal: :Blood 2008
Harukiyo Kawamura Xiujuan Li Katsutoshi Goishi Laurens A van Meeteren Lars Jakobsson Stéphanie Cébe-Suarez Akio Shimizu Dan Edholm Kurt Ballmer-Hofer Lena Kjellén Michael Klagsbrun Lena Claesson-Welsh

Vascular endothelial growth factor (VEGF)-A regulates vascular development and angiogenesis. VEGF isoforms differ in ability to bind coreceptors heparan sulfate (HS) and neuropilin-1 (NRP1). We used VEGF-A165 (which binds HS and NRP1), VEGF-A121 (binds neither HS nor NRP1), and parapoxvirus VEGF-E-NZ2 (binds NRP1 but not HS) to investigate the role of NRP1 in organization of endothelial cells i...

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Journal: :Journal of virology 2007
Jae-Kyung Hyun Fasséli Coulibaly Adrian P Turner Edward N Baker Andrew A Mercer Alok K Mitra

Orf virus, the prototype parapoxvirus, is responsible for contagious ecthyma in sheep and goats. The central region of the viral genome codes for proteins highly conserved among vertebrate poxviruses and which are frequently essential for viral proliferation. Analysis of the recently published genome sequence of orf virus revealed that among such essential proteins, the protein orfv075 is an or...

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Journal: :Journal of virology 2000
V Fachinger T Schlapp W Strube N Schmeer A Saalmüller

The prophylactic application of inactivated parapox ovis viruses (Baypamun; Bayer AG, Leverkusen, Germany) has been shown to reduce efficiently the outbreak of stress-mediated diseases in different species. However, little is known about the basic mechanism behind this observed stimulatory property. We therefore tested eight inactivated poxvirus strains belonging to three different genera (Orth...

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