Hands often become contaminated with respiratory viruses, either directly or through contact with contaminated surfaces. Spread of such viruses could then occur by touching the nasal mucosa or the conjunctivae. In this quantitative study, we compared the survival of mucin-suspended human parainfluenza virus 3 (HPIV-3) and rhinovirus 14 (RV-14) and the transfer of the viruses to and from the fin...

Novel sialidase inhibitors 11 having an α-acylaminoamido group at the C-4 position of Neu5Ac2en 1 against human parainfluenza virus type 1 (hPIV-1) were synthesized using one-pot isocyanide-based four-component condensation, and their inhibitory activities against hPIV-1 sialidase were studied. Compound 11b showed inhibitory activity (IC(50)=5.1 mM) against hPIV-1 sialidase. The degree of inhib...

Respiratory syncytial virus (RSV) and the human parainfluenza viruses (PIVs) are enveloped nonsegmented negative-strand RNA viruses of the paramyxovirus family. RSV is the leading cause of severe viral respiratory disease in infants and children, and in the United States RSV is responsible for 73,000 to 126,000 annual hospitalizations of infants younger than 1 year of age (1). Two antigenic sub...

Exacerbations of chronic bronchitis are often preceded by symptoms of infection of the upper respiratory tract, but little is known of the frequency with which they are precipitated by virus infections. There is evidence that bronchitics develop severe illness when infected with influenza A virus (Tyrrell, 1952; Walker, Douglas, Leckie, Pines, and Grant, 1958; Louria, Blumenfeld, Ellis, Kilbour...

199 human serum samples were examined for the presence of myxovirus parainfluenza 3 (mpi 3)haemagglutination inhibition (hi) antibodies. or tbe total male sera, 75% and female 70.52% had hi antibody titers of t:32 or greater. the percentage of positive samples increased according to the age grouping of the human beings. these results indicate that mpi 3 virus infection is widespread among the h...

  Background :Respiratory viruses are the leading cause of respiratory tract infections among children and are responsible for causing morbidity and mortality worldwide. This study was performed to detect viruses in children with respiratory infections and describe their epidemiology and clinical characteristics.   Methods : In this descriptive cross sectional study, throat swabs and wash speci...

Abstract Background and Aims: To identify and isolation of viruses a susceptible cell is need which can be primary or line. The use of primary cells is laborious, time consuming and expensive, while the use of cell lines is much easier and faster. IRKHBK cell line was originated from primary cells of bovine kidney by continuous passage. The aim of this study was to introduce the IRKHBK cell ...

199 human serum samples were examined for the presence of myxovirus parainfluenza 3 (mpi 3) haemagglutination inhibition (hi) antibodies. or tbe total male sera, 75% and female 70.52% had hi antibody titers of t:32 or greater. the percentage of positive samples increased according to the age grouping of the human beings. these results indicate that mpi 3 virus infection is widespread among the ...

The purpose of this study was to determine the seropositivity circulating viral pathogens and their association with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seropositivity. In a cross-sectional design, inhabitants (aged 10–60 years) slum surrounding non-slum areas Dhaka Chattogram Metropolitan cities in Bangladesh were enrolled from October 2020 February 2021. Antibodies SA...