aim : the aim of this study was to evaluate the mortality rates and trends from gastrointestinal (gi) cancer in iranian population from 1995 to 2003. background : cancer is the third most common cause of death in iran. gastrointestinal cancer is the most important causes of mortality due to cancer. the cancer mortality data is important to monitor the effects of screening program, earlier diagn...

Metastatic carcinoma of the pancreas from another primary site is uncommon and it accounts for 2-5% of all pancreatic cancer cases. We reported the case of one patient with pancreatic metastasis from colon carcinoma in the past and would like to add another six cases of pancreatic metastases from different types of cancer. The diagnosis of cancer metastatic to the pancreas should be suspected w...

Among pancreatic cystic lesions, mucinous neoplasm (MCN) and intraductal papillary (IPMN) of the pancreas are precursor lesions adenocarcinoma. IPMN is characterized by proliferation mucin-producing epithelial cells that exhibit various degrees dysplasia. classified as main duct type (MD-IPMN), mixed branch (BD-IPMN) according to location involvement, into four histological subtypes (gastric, i...

Apoptosis can be triggered in two different ways, through the intrinsic or the extrinsic pathway. The intrinsic pathway is mediated by the mitochondria via the release of cytochrome C while the extrinsic pathway is prompted by death receptor signals and bypasses the mitochondria. These two pathways are closely related to cell proliferation and survival signaling cascades, which thereby constitu...

In industrial workers, formaldehyde exposure has been associated with cancer of the nasal cavities, nasopharynx, prostate, lung, and pancreas; however, these associations are inconsistent and remain controversial. Animals exposed to formaldehyde show excesses of nasal cancer. In an extended follow-up of a large cohort of formaldehyde-exposed workers, the authors evaluated mortality from solid c...

PURPOSE Discriminant markers for pancreatic cancer detection are needed. We sought to identify and validate methylated DNA markers for pancreatic cancer using next-generation sequencing unbiased by known targets. EXPERIMENTAL DESIGN At a referral center, we conducted four sequential case-control studies: discovery, technical validation, biologic validation, and clinical piloting. Candidate ma...

The research included isolation and purification of Trypsin from serum patient with pancreatic cancer, estimation its molecular weight by using the two techniques gel filtration (using sephadex G-50) electrophoresis SDS). Therefore; it was noted that proteinous peak isolated ammonium sulfate solution is saturated (65%) had apparent (27000) Dalton. study (40) patients pancreas cancer their ages ...

Smoking is, and long has been, more prevalent among Maori than non-Maori in New Zealand. Lung cancer, but not other smoking-related cancers, is known to be markedly more common among Maori than non-Maori. Incidence and mortality data from the New Zealand Cancer Registry for cancers of the mouth/pharynx, oesophagus, pancreas, larynx, kidney and bladder, as well as lung/pleura, during the period ...

Diabetes and cancer are two heterogenous diseases which rapidly increasing in prevalence globally. A link between these non-communicable was first identified over 100 years ago however, recent epidemiological studies advances genomic research have provided greater insight into the association diabetes cancer. Epidemiological suggested that individuals with an increased risk of several types (in...

OBJECTIVES An imbalance of free radicals and scavenging processes has been implicated in the pathogenesis of pancreatic tissue injury. Gradual decreases in antioxidant enzyme expression in pancreatic cells from normal pancreas to chronic pancreatitis to pancreatic cancer have been reported. Zinc is one of the components of antioxidant enzymes and may play a role in the pathogenesis of pancreati...