Ginseng, the famous plant drug, has been used as an expensive traditional medicine in oriental countries. The main ginseng plants of this drug are Panax ginseng C. A. MEYER, P. quinquefolium L. (American ginseng), P. natoginseng (Sanchi ginseng, or Tienchi ginseng), P. japonicus, and other species of Panax genus. One of physiological activity materials of ginseng plants is saponin (ginsenoside)...

The root of Panax ginseng C.A. Meyer has been shown to induce nitric oxide (NO) release resulting in a hypotensive effect. However, the main active component contributing to vascular endothelium relaxation remains uncertain. In this study, we hypothesized that multiple components of ginseng extract might have combinatory effects providing greater health benefits than a single ginsenosides. To t...

Chinese ginseng, Korean red ginseng, Panax ginseng: Panax spp. including P. ginseng C.C. Meyer and P. quinquefolius L., excluding Eleutherococcus senticosus) Natural Standard Bottom Line Monograph, Copyright © 2008 (www.naturalstandard.com). Commercial distribution prohibited. This monograph is intended for informational purposes only, and should not be interpreted as specific medical advice. Y...

Panax ginseng exhibits pleiotropic beneficial effects on cardiovascular system, central nervous system, and immune system. In the last decade, numerous preclinical findings suggest ginseng as a promising therapeutic agent for diabetes prevention and treatment. The mechanism of ginseng and its active components is complex and is demonstrated to either modulate insulin production/secretion, gluco...

Ginseng roots (Panax ginseng CA Meyer) have been used traditionally for the treatment, especially prevention, of various diseases in China, Korea, and Japan. Both experimental and clinical studies suggest ginseng roots to have pharmacological effects in patients with life-style-related diseases such as non-insulin-dependent diabetic mellitus, atherosclerosis, hyperlipidemia, and hypertension. T...

Treatment of rats with a single oral dose (10–30 mg/kg) of a crude Panax ginseng extract of unknown ginsenoside content has been reported to modestly increase hepatic microsomal cytochrome P450-mediated aminopyrine N-demethylation activity. In the present study, we compared the effect of P. ginseng and Panax quinquefolius extracts on rat hepatic CYP2B1, CYP3A23, and CYP1A2 gene expression. Adul...

High hydrostatic pressure (HHP) is an attractive method for food preservation due to resulting improvements in the quality characteristics of foods, in addition to microbial inactivation. This study aimed at improving the nutraceutical potential of red ginseng (Panax ginseng C.A. Meyer). HHP treatment of 600 MPa for 1 min at room temperature in conjunction with conventional steaming and drying ...

aceae), has been heat-processed to improve its medicinal efficacies in Korea based on the long history of ethnopharmacological evidence. Although the increasing body of evidence supports that Maillard reaction products (MRPs) are implicated in the increased activity by heat treatment in various crude drugs or foods, the effect of Maillard reaction on the active components of ginseng and biologi...