background: the incidence of ulcerative colitis (uc) is rising in populations with western-style diet, rich in fat and protein, and low in fruits and vegetables. in the present study, we aimed to evaluate the association between dietary protein intakes and the risk of developing incident uc.   methods : sixty two cases of uc and 124 controls were studied using country-specific food frequency qu...

The anti-inflammatory actions of vitamin D have long been recognized and its importance in modulating colon cancer and colitis development is becoming apparent. The vitamin D receptor (VDR) is downregulated in human ulcerative colitis and colitis-associated cancer (CAC); however, its status in murine models of colitis has yet to be explored. Snail and Snail2, zinc-finger transcription factors r...

The aetiology of ulcerative colitis is unknown. Two patients without pre-existing inflammatory bowel disease in whom end colostomy for faecal incontinence was complicated by diversion colitis in the defunctioned rectosigmoid colon, are described. In both instances, colitis with the clinical, colonoscopic, and microscopic features of ulcerative colitis developed about a year later in the previou...

â  background : primary sclerosing cholangitis (psc) is a chronic cholestatic disease that results in segmental stenosis of the bile ducts, cholestasis and fibrosis. during the previous two decades, patients with steroid responsive psc have been presented in a few case reports and studies. this study aims to evaluate and compare igg4 levels in patients with ulcerative colitis (uc), with and wit...

background: musculoskeletal manifestations (msm) of inflammatory bowel diseases (ibds) are usually the most frequent extraintestinal manifestations. however, they are not paid enough attention during regular office visits. this cross-sectional study aimed to draw a clinical picture of msm and their relationships with other findings in patients with ibd. materials and methods: patients of our ib...

background and objectives: baneh tree or pistacia atlantica subsp. kurdica is an endemic plant of iran which belongs to anacardiaceae family. it has various traditional uses including astringent and anti-diarrheal as well as improving some of the symptoms of gastrointestinal upsets. in this study we decided to investigate the effects of various fractions of baneh gum with different doses in an ...

Amongst extraintestinal manifestations (EIM) occurring in IBD patients, rheumatologic manifestations are the most frequent. Understanding the relationships between arthritis and colitis is a prerequisite to improving the management of these patients. Microbiota of patients with IBD or rheumatologic diseases, like spondyloarthritis (SpA) is modified compared to healthy individual. Thus, we have ...

Dysregulated immune responses to the gut microbiota are believed to be the driving force in the development of inflammatory bowel diseases. Even with combined modern and newer diagnostic technologies, it is difficult to accurately differentiate colonic inflammatory bowel disease, namely ulcerative colitis and Crohn’s colitis. Regardless of current advanced clinical and pathological criteria ava...