N-Allyl-N-methyl-2-aminopropane (AMAP) is a relatively simple tertiary amine that has a chiral center at the pyramidal nitrogen. Racemization occurs by inversion-rotation at nitrogen. For each AMAP enantiomer, conformational exchanges occur via isolated rotation about carbon-nitrogen and carbon-carbon bonds. The 1H and 13C{1H} dynamic NMR (DNMR) spectra of AMAP show a higher temperature decoale...

BACKGROUND A variant in the promoter of the human uncoupling protein 2 (UCP2) gene, the G-866A polymorphism, has been associated with future risk of coronary heart disease events, in those devoid of traditional risk factors and in those suffering from diabetes. We thus examined the impact of the G-866A polymorphism on 5-year survival in a cohort of 901 post-myocardial infarction patients, and t...

Case control study was used ,with healthy individual control(n=20)and Glanzmannthrombastheniapatients(n=15). The diagnosis depending on the clinical , hematological parameters and molecularanalysis.All patients were severe bleeding symptoms with normal Hemoglobin plateles count ,andprolonged time.It successfully identified three SNP in ITGA2B gene first c.2653 T>G (rs5911)was presentedwith geno...

Celiac disease (CD) remains one of the most significant autoimmune diseases worldwide. The pathogenesis of CD is not clearly understood and is probably attributed to genomic variations and host genetic make-up. Case-control and cohort studies of the association between the TNF-α -308 G > A (rs1800629) polymorphism and CD susceptibility have yielded inconsistent results. In this study, PubMed, E...

Body measurement and meat quality traits play important roles in the evaluation of productivity and economy in cattle, which are influenced by genes and environmental factors. PRKAG2, which encodes the γ2 regulatory subunit of AMPK, is associated with key metabolic pathways in muscle. We detected bovine PRKAG2 gene polymorphisms and analyzed their associations with body measurement and meat qua...

background: acromegaly is associated with increased morbidity and mortality related to cardiovascular diseases. leptin (lep) and leptin receptor (lepr) gene polymorphisms can increase cardiovascular risks. the aim of this study was to investigate association between the frequencies of lep and lepr gene polymorphisms and subclinical atherosclerosis in acromegalic patients. methods: forty-four ac...

In the previous lecture, we proved that if f is a permutation and B is an (S,)-hardcore predicate for f then G : x → f (x), B(x), which maps n bits to n + 1 bits, is (S,) pseudorandom. We then started investigating the performance of the iterative application of G, namely G (k) defined as in figure 1. B(x)) B(f(x))) B(f ((2)) (x))) B(f ((k-1)) (x))) f ((k)) (x)) xx GG GG GG GG Figure 1: Definit...

Metabolic syndrome (MetS) is characterized by a cluster of cardiovascular risk factors that include: abdominal obesity, dyslipidaemia, hypertension, insulin resistance and impaired glucose tolerance. Recent genome wide association studies have identified several susceptibility regions involved in lipid metabolism that are also associated with MetS. We have explored the association of 9 genetic ...

BACKGROUND The aim of the present study was to investigate the association between tumor necrosis factor-alpha (TNF-α) gene G-238A polymorphism and risk of coronary artery disease (CAD) using a meta-analytical approach. METHODS The PubMed and Embase databases were searched for relevant publications up to January 13, 2015. Four authors (XPH, XDZ, XTZ, and ZJZ) independently selected the studie...

The average turbid optical properties of the N-isopropylacrylamide (NIPA) polymer solution entrapped inside a polyacrylamide hydrogel (called an NIPA/PAAM gel system) were studied using a multiwavelength oblique-incidence reflectometer. The turbidity of such a system can be drastically changed by simply switching the temperature from below the low critical solution temperature of the NIPA, arou...