Extensive analyses of mice carrying null mutations in paired box 7 (Pax7) have confirmed the progressive loss of the satellite cell lineage in skeletal muscle, resulting in severe muscle atrophy and death. A recent study using floxed alleles and tamoxifen-induced inactivation concluded that after 3 wk of age, Pax7 was entirely dispensable for satellite cell function. Here, we demonstrate that P...

Satellite cells are situated beneath the basal lamina that surrounds each myofiber and function as myogenic precursors for muscle growth and repair. The source of satellite cell renewal is controversial and has been suggested to be a separate circulating or interstitial stem cell population. Here, we transplant single intact myofibers into radiation-ablated muscles and demonstrate that satellit...

Low Earth Orbits (LEO) satellites are used for public communication and for scientific purposes. These satellites provide opportunities for investigations for which alternative techniques are either difficult or impossible to apply. Ground stations have to be established in order to communicate with such satellites. Usually these satellites communicate with ground stations at S-band. The commun...

Adult skeletal muscle possesses a resident stem cell population called satellite cells, which are responsible for tissue repair following damage. Satellite cell migration is crucial in promoting rapid tissue regeneration, but it is a poorly understood process. Furthermore, the mechanisms facilitating satellite cell movement have yet to be elucidated. This study investigates the process of satel...

Androgen treatment can enhance the size and strength of muscle. However, the mechanisms of androgen action in skeletal muscle are poorly understood. This review discusses potential mechanisms by which androgens regulate satellite cell activation and function. Studies have demonstrated that androgen administration increases satellite cell numbers in animals and humans in a dose–dependent manner....

A purification scheme for satellite DNA containing chromatin from mouse liver has been developed. It is based on the highly condensed state of the satellite chromatin and also takes advantage of its resistance to digestion by certain restriction nucleases. Nuclei are first treated with micrococcal nuclease and the satellite chromatin enriched 3-5 fold by extraction of the digested nuclei under...

Received Jul 5, 2014 Revised Nov 11, 2014 Accepted Nov 22, 2014 In this paper, an algorithm was presented to control the satellite attitude in orbit in order to reduce the fuel consumption and increase longevity of satellite. Because of proper operation and simplicity, fuzzy controller was used to save fuel and analyze the uncertainty and nonlinearities of satellite control system. The presente...

IN THE NEWS FOCUS STORY “WEATHER forecasts slowly clearing up” (9 November, p. 734), R. Kerr nicely summarizes how the growing improvement in prediction is coming from a focus on “more computer power, the assimilation of radar observations, and more physically realistic models.” He emphasizes that better assimilation of satellite data is a key element of improved forecasting. Unfortunately, the...

INTRODUCTION Muscle stem cells termed satellite cells are essential for muscle regeneration. A central question in many neuromuscular disorders is why satellite cells are unable to prevent progressive muscle wasting. We have analyzed muscle fiber pathology and the satellite cell response in Pompe disease, a metabolic myopathy caused by acid alpha-glucosidase deficiency and lysosomal glycogen ac...

We have studied the origin of muscle satellite cells in embryos of Xenopus laevis. Fate mapping at the open neural plate stage was carried out using orthotopic grafts from transgenic embryos expressing GFP. This shows that most satellite cells originate from the dorsolateral plate rather than from the paraxial mesoderm. Specification studies were made by isolation of explants from the paraxial ...