نتایج جستجو برای: p4

تعداد نتایج: 5771  

2012
Marta J Siemieniuch Ewelina Jursza Anna Z Szostek Dariusz J Skarzynski Alois Boos Mariusz P Kowalewski

BACKGROUND Until recently, the corpus luteum (CL) was considered to be the main source of progesterone (P4) during pregnancy in the domestic cat (Felis catus). However, other possible sources of P4 have not been ruled out. Although feline placental homogenates were found to be capable of synthesizing P4, expression of the respective steroidogenic enzymes has not been investigated at the molecul...

2013
Vincent A. van der Mark Ronald P.J. Oude Elferink Coen C. Paulusma

P4 ATPases catalyze the translocation of phospholipids from the exoplasmic to the cytosolic leaflet of biological membranes, a process termed "lipid flipping". Accumulating evidence obtained in lower eukaryotes points to an important role for P4 ATPases in vesicular protein trafficking. The human genome encodes fourteen P4 ATPases (fifteen in mouse) of which the cellular and physiological funct...

2012
Weiyan Cai Masahiro Sokabe Ling Chen

Evidence exists for a gender difference in the vulnerability to either stroke or traumatic brain injury (TBI) in humans. For example, pre-menopausal women with the high serum levels of ovarian hormones estrogen (E2) and progesterone (P4) have a lower risk of stroke (Kannel et al., 1994; Sacco et al., 1997) and a better outcome following stroke (Thorvaldsen et al., 1995) or TBI (Groswasser et al...

Journal: :Journal of animal science 1992
L D Vailes S P Washburn J H Britt

Two experiments were conducted to determine how steroid milieus and pregnancy affect sexual behavior. Experiment 1 was arranged as a Latin square with five ovariectomized cows and five steroid milieus: no steroid (N); progesterone (P4); estradiol benzoate (EB); P4 + EB; and P4 followed by EB (P4:EB). Progesterone was administered via pessary (2 g of P4) for 5 d and EB was injected (1 mg i.m.) o...

2015
Hillary Adams Sandra L. Petersen

The anteroventral periventricular (AVPV) nucleus of the hypothalamus integrates estradiol (E2) and progesterone (P4) feedback signals from the ovaries to stimulate gonadotropin releasing hormone (GnRH) neurons and trigger an ovulatory surge in luteinizing hormone (LH). E2 maintains the daily cyclic LH surge and P4 quickly amplifies the surge and limits it to one day. P4 amplification of the sur...

2003
Kaj Tesink Hans Kok

This paper discusses a project carried out at the Digital Laboratories of the Twente University of Technology. The purpose of the project was twofold: Firstly, to develop a digital hardware design and test method. Secondly, to build a hardware interpreter for an intermediate code of Pascal, the so'called P4 code. The implemented P4 machine is based on AM2901 bit slices. During the project a P4 ...

Journal: :international journal of health policy and management 2015
jorge bernstein ricardo la valle

the concept of quaternary prevention (p4) refers to the idea that medicine has acquired the ability to damage through the proper exercise. family medicine or general practice has the duty of recovering the ethical values and the exercise of a profession with the doctor-patient relationship serving to people’s humanity. in the fourth congress of family and community medicine, held in montevideo ...

Journal: :The Biochemical journal 1990
A Höer D Höer E Oberdisse

We have previously shown that Ins(1,3,4,5)P4 is degraded to Ins(1,4,5)P3 by a soluble Ins(1,3,4,5)P4 3-phosphatase from pig brain [Höer, Kwiatkowski, Seib, Rosenthal, Schultz & Oberdisse (1988) Biochem. Biophys. Res. Commun. 154, 668-675]. Here we present some properties of this enzyme using [5-32P]Ins(1,3,4,5)P4 as substrate. The molecular mass, estimated by gel filtration chromatography on a ...

Journal: :Oncology reports 2013
Xiaofei Zhu Yue Han Zhuyuan Fang Wenzhong Wu Mingde Ji Fengmeng Teng Wei Zhu Xuewen Yang Xuemei Jia Chunbing Zhang

Progesterone, also known as P4 (pregn-4-ene-3, 20-dione), is a C-21 steroid hormone involved in the female menstrual cycle, pregnancy (supports gestation) and embryogenesis of humans and other species. Despite the physiological effects, P4 is also effective for the treatment of numerous pathological states, such as multiple sclerosis, rheumatoid arthritis and systemic lupus erythematosus as wel...

Journal: :Physiological genomics 2016
Sreenath Chandran Michael T Cairns Margaret O'Brien Enda O'Connell Kaveh Mashayekhi Terry J Smith

A transcriptomic analysis of cultured human uterine smooth muscle cells (hUtSMCs) was performed to examine gene expression profiles in smooth muscle in an environment containing the two major steroid hormones that regulate the human myometrium in physiological states associated with estrous, pregnancy, labor, and pathophysiological states such as leiomyoma and endometrial cancer. hUtSMCs were t...

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