The following is a guide to the more important naturally occurring fatty acids with hydroxy, epoxy (furanoid), methoxy and oxo substituents, but it is not intended to be a comprehensive list. The prostaglandins and other eicosanoids and the plant oxylipins are in essence fatty acids with additional oxygenated functional groups, but these are discussed elsewhere in this website. Similarly, hydro...

Jasmonates, derivatives of jasmonic acid, are lipid-derived oxylipins with cyclopentanone ring, produced as a result dioxygenation mediated by lipoxygenases. The biosynthesis acid is catalysed series different enzymes, starting from lipoxygenase, allene oxide synthase, cyclase and 12-oxophytodienoic reductase to the final three rounds β-oxidation. Consequently, few metabolites known jasmonates ...

The omega-3 polyunsaturated fatty acids (n-3 PUFAs), eicosapentaenoic acid (EPA) and docosahexaenoic (DHA), mediate inflammation in large part by affecting pro-inflammatory anti-inflammatory/pro-resolving oxylipin concentrations. Common gene variants are thought to underlie the inter-individual variation levels response n-3 PUFA supplementation, which turn is likely contribute overall heterogen...