Bile acids have been implicated in cholestatic liver damage, primarily due to their detergent effect on membranes and induction of oxidative stress. Gangliosides can counteract these harmful effects by increasing the rigidity of the cytoplasmic membrane. Induction of haem oxygenase (HMOX) has been shown to protect the liver from increased oxidative stress. The aim of this study was to determine...

The AhpC subunit of the Bacillus subtilis alkyl hydroperoxide reductase was identified as a general stress protein induced in response to heat or salt stress or after entry of the organism into the stationary phase. The ahp operon, encoding the two subunits AhpC and AhpF, was cloned and localized between the gntRKPZ operon and the bglA locus. Two-dimensional gel analyses revealed an especially ...

Resveratrol, an important antioxidant found in grapes and wine, is likely to contribute to red wine's potential to prevent human cardiovascular disease. In addition to its known (direct) antioxidant effect, we have found that resveratrol also regulates the gene expression of pro-oxidative and anti-oxidative enzymes in human endothelial cells. NADPH oxidases (Nox) are the predominant producers o...

heavy metal accumulation in plants causes induction of oxidative stress. plants have severaldefense systems involved in detoxifying free radicals. in the present research we treated the 15 d.seedlings of b. napus grown in pots with different concentrations of cadmium (0, 10, 50 and 100 μm) ascdcl2. after 3 weeks we measured malondealdehyde (mda) content in leaves of treated plants as anindicati...

BACKGROUND/AIM Silybin is the main component of silymarin with antioxidant, anti-inflammatory and cytoprotective actions. Our aim was to compare the effect of silybin used as single substance, silybin-phosphatidylcholine complex (SilPho), and derivatives of silybin (MannpSil, GalpSil, GlcpSil, LactpSil) on MKN28 and HepG2 cell viability and cell death, in vitro, after induction of oxidative str...

the use o f a smal l dose of neostigmine during i nduction of anesthesia provides many valudable clinical manifestation which have been discussed in detail . i believe this method of anesthesia might be desirable in emergency situations and whenever the ventilator is not avai labl e .

HSP70 and heme oxygenase-1 (HO-1) are thought to be markers of cell injury and oxidative stress, respectively. We have immunolocalized these proteins in the spinal cord at 1-14 days after contusion. HSP70 and HO-1 were co-induced in glia and macrophages within the injured segment at all time points. This co-induction may reflect complementary functions that serve to protect these cells as they ...

In this study, the kinetics of gas hydrate formation in the presence of tetra-n-butyl ammonium fluoride (TBAF) and cetyl trimethyl ammonium bromide surface active ingredient (CTAB) with zinc nano oxide (ZnO) are investigated and the most important kinetic parameters of hydrate formation such as their induction time and storage capacity were measured. The kinetic experiments were carried out in ...

One of the most pressing concerns to global public health is emergence drug-resistant pathogenic microorganisms due increased unconscious antibiotic usage. With rising resistance, existing antimicrobial agents lose their effectiveness over time. This indicates that newer and more effective methods should be investigated. Many studies have shown micro-/nanorobots exhibit promise in treatment mic...

Introduction. Chronic respiratory diseases are one of the most common types non-communicable and an important problem our time. The induction oxidative stress, chronic inflammation hypoxia, which underlie pathogenesis bronchopulmonary system, can be determined at cellular molecular level by impaired mitochondrial functioning. Aim. This review is devoted to prospects for assessing functional sta...