Overactive bladder (OAB) is a prevalent condition characterized by lower urinary tract symptoms (LUTS). Age, education, income, marital status, sleep, and emotional problems have been associated with OAB; however, conflicting results exist. The present study was conducted to estimate the prevalence of OAB and comprehensively analyze its associated factors in a large cross-sectional, population-...

Overactive bladder (OAB) is a clinical symptom complex whose hallmark is the symptom of urinary urgency, usually accompanied by frequency and nocturia, with or without urgency incontinence. Historically, urodynamics (UDS) evaluation has not been recommended in the initial evaluation of OAB, since it is defined primarily by clinical symptoms. As the pathophysiology of the OAB complex has become ...

Abstract Background Contemporary studies have discredited the methods used to exclude urinary tract infection (UTI) when treating overactive bladder (OAB). Thus we must revisit OAB phenotype check that UTI has not been overlooked. Aims To examine differences in cytokines IL6 and lactoferrin patients compared controls, with references microscopy of urine enhanced quantitative culture. Methods A ...

Objective: The definite cause of overactive bladder (OAB), which negatively affects the quality life patients, is unknown. This study aims to provide evidence for inflammatory process in patients with OAB whose etiology has not been fully elucidated. Material and Methods: included 154 people diagnosis 131 as controls. was conducted retrospectively, cross-sectionally between April 2015 2020. dat...

OBJECTIVE To compare the quality of life (QoL) among 3 groups of Thai postmenopausal women with an overactive bladder (OAB), diabetes, and without these conditions. MATERIAL AND METHOD A total cross-sectional cohort of 180 postmenopausal women aged 48-60 years (60 had OAB, 60 diabetes and 60 controls) were recruited from the menopause clinic and diabetes clinic of Hatyai regional hospital bet...

Prevalence, pathophysiology, diagnostic and therapeutic approaches of urinary incontinence are well studied in women, however studies on male urinary incontinence focus on incontinence following surgery of the bladder or prostate, predominantly incontinence after radical prostatectomy. Aging men suffer from incontinence; most frequently urge incontinence (Overactive bladder) nearly as often as ...

Hypothesis / aims of study Fesoterodine is a relatively novel antimuscarinic agent for the treatment of overactive bladder (OAB) [1]. When administered orally, fesoterodine is rapidly and extensively converted to its active metabolite, 5-hydroxymethyl tolterodine (5-HMT), which is also an active metabolite of tolterodine [2]. Our recent study with radioligand binding assay has shown that fesote...

Contemporary, the management of overactive bladder (OAB), a medical condition characterized by urgency, with or without urge urinary incontinence, frequency and nocturia, in absence of genitourinary pathologies or metabolic factors that could explain these symptoms, is complex, and a wide range of conservative treatments has been offered, including bladder training, biofeedback, behavioral chan...

OBJECTIVES To evaluate the role of cystometry in the diagnostic evaluation of patients with symptoms of overactive bladder, by comparing the treatment outcome in those with and without urodynamically proven bladder instability. METHODS Prospective observational study performed at Urogynaecology Division, the Kidney Center Post-Graduate institute of nephro-urology, Karachi. Forty six patients ...

OBJECTIVES Recent studies have shown that chronic inflammation is involved in overactive bladder (OAB) syndrome. OAB could be a subtype of neurogenic inflammation. This pilot study investigated serum adipokine levels in patients with OAB refractory to antimuscarinic therapy. METHODS Thirty consecutive patients with OAB-dry (n = 16) or OAB-wet (n = 14) refractory to previous antimuscarinic tre...