As a society we are now more connected than ever before. Citizens interact with each other and form virtual communities based on a common interest or being involved in certain cultural, political, intellectual, or other issues. Volunteered Geographic Information (VGI) is generated when citizens annotate content generated by them in social media and on smart devices. OpenStreetMap is a famous ex...

Online social media (OSM) has a enormous influence in today’s world. Some individuals view OSM as fertile ground for abuse and use it to disseminate misinformation and political propaganda, slander competitors, and spread spam. The crowdturfing industry employs large numbers of bots and human workers to manipulate OSM and misrepresent public opinion. The detection of online discussion topics ma...

The angiotensin II type 1 (AT1) receptor, transforming growth factor beta1 (TGFbeta1) and Oncostatin M (OSM) control key pathways that may be important during placentation. Although interactions between them exist in other tissues, trophoblast cells have not been investigated. Extravillous trophoblast cells, SGHPL-4, were stimulated with 10 ng/ml TGFbeta1 +/- 100 ng/ml OSM for 24 h. Real-time P...

Oncostatin M (OSM) is a 28-kD glycoprotein recently identified as a growth factor for human multiple myeloma cells. It belongs to a family of distantly related cytokines that includes interleukin 6, ciliary neurotrophic factor, leukemia-inhibitory factor, and interleukin 11. These cytokines initiate signaling by inducing either homodimerization of gp130 or heterodimerization of gp130 with leuke...

Object-substitution masking (OSM) refers to reduced target discrimination when the target is surrounded by a sparse mask that does not overlap with the target in space but trails it in time. In four experiments, we used a novel paradigm to investigate the extent of processing of a masked target in OSM. We measured response-compatibility effects between target and mask, both when the offsets wer...

The appearance of OpenStreetMap (OSM) in 2004 sparked a phenomenon known as Volunteered Geographic Information (VGI). Today, VGI comes in many flavours (e.g. toponyms, GPS tracks, geo-tagged photos, micro-blogging or complete topographic maps) and from various sources. One subject that has attracted research interest from the early days of VGI is how good such datasets are and how to combine th...

Inflammatory response and articular destruction are common symptoms of osteoarthritis. Cysteine-rich 61 (CCN1 or Cyr61), a secreted protein from the CCN family, is associated with the extracellular matrix involved in many cellular activities like growth and differentiation. Yet the mechanism of CCN1 interacting with arthritic inflammatory response is unclear. This study finds CCN1 increasing ex...

BACKGROUND On Late Cretaceous Tethyan upwelling sediments from the Mishash/Ghareb Formation (Negev, Israel), bulk geochemical and biomarker analyses were performed to explain the high proportion of phosphates in the lower part and of organic matter (OM) preserved in upper parts of the studied section. The profile is composed of three facies types; the underlying Phosphate Member (PM), the Oil S...

The acute phase response is traditionally characterized by hepatic synthesis of proteins as an inflammatory response to injury, with interleukin-6 (IL-6) being the key mediator. In contrast, microarray studies in human renal transplant implantation biopsies indicate a strong acute phase response in the deceased donor kidney, associated with a significant upregulation of oncostatin M receptor be...