The wall shear stress (WSS) of flowing blood and the circumferential strain (CS) driven by the pressure pulse interact to impose a dynamic force pattern on endothelial cells (ECs) which can be characterized by the temporal phase angle between WSS and CS, a quantity which varies significantly throughout the circulation. To study the interaction of WSS and CS on endothelial production of vasodila...

To describe circadian blood pressure (BP) patterns and linear interdialytic changes, a model was developed to describe simultaneously both the straight line change and oscillatory variation in BP and heart rate over an interdialytic interval in hemodialysis patients. Using this trended cosinor model, we simultaneously compared the impact of mean level of BP, linear changes over the interdialyti...

Circadian rhythms are prevalent in most organisms. Even the smallest disturbances in the orchestration of circadian gene expression patterns among different tissues can result in functional asynchrony, at the organism level, and may to contribute to a wide range of physiologic disorders. It has been reported that as many as 5%-10% of transcribed genes in peripheral tissues follow a circadian ex...

Parameters of system dynamics models are subject to uncertainty, so sensitivity analysis is an important task for the reliability of simulation results. Since system dynamics is a behavior-oriented simulation discipline, sensitivity of behavior pattern measures, such as equilibrium level or oscillation amplitude to the model parameters should be evaluated in order to explore the effects of para...

Pattern-forming fronts are often controlled by an external stimulus which progresses through a stable medium at a fixed speed, rendering it unstable in its wake. By controlling the speed of excitation, such stimuli, or “triggers,” can mediate pattern forming fronts which freely invade an unstable equilibrium and control which pattern is selected. In this work, we analytically and numerically st...

Using Dirac equation together with the Wigner distribution function,the trembling motion,known as Zitterbewegung effect,of moving electrons in quasi-one-dimensional relativistic quantum plasma is theoretically investigated.The matrix used to calculate mean values of position and velocity operators for a gas electrons.It found that oscillatory behavior measurable quantities could be associated e...

Projection neurons of the substantia nigra reticulata (SNr) convey basal ganglia (BG) processing to thalamocortical and brain stem circuits responsible for movement. Two models try to explain pathological BG performance during Parkinson disease (PD): the rate model, which posits an overexcitation of SNr neurons due to hyperactivity in the indirect pathway and hypoactivity of the direct pathway,...

Food 3D printing allows for the production of personalised foods in terms shape and nutrition. In this study, we examined whether protein-, starch- fibre-rich fractions extracted from faba beans can be combined to produce fibre- protein-rich printable food inks extrusion-based printing. Small amplitude oscillatory shear measurements were used characterise while compression tests scanning electr...

Enhancement of heat and mass transfer and decrease of energy dissipation are great necessities of the evolution of fluid flow devices. Utilizing oscillatory or pulsatile fluid flow for periodic disturbing of velocity and thermal boundary layers is one of the methods with exciting results. Passive methods of generating oscillatory flow are preferred to active methods because of simplicity, no ne...

PURPOSE To correlate retinal function with vascular response to flicker light in normotensive patients with diabetes without diabetic retinopathy (DR). METHODS Twenty-eight normotensive patients with diabetes (11 with type 1, 17 with type 2) without DR and 28 sex- and age-matched healthy control subjects underwent color vision and contrast sensitivity testing, pattern, full-field, and multifo...