In this work we highlight a possible synergistic anti-Candida effect between Melaleuca alternifolia, Origanum vulgare and Pelargonium graveolens essential oils and the antifungal compound Amphotericin B. The antifungal activity was assessed using the agar dilution method in eleven Candida strains. The results obtained indicate the occurrence of a synergistic interaction between the essential oi...

Mycophenolic acid is a secondary extracellular metabolite of Penicillium strains with numerous pharmaceutical properties such as antibiotic and immunosuppressive uses. The aim of this work is the survey of the effect of phenylglyoxal and n-ethylmaleimide concentration in culture medium on mycophenolic acid production by Penicillium brevi-compactum ATCC16024 was investigated. Batch submerged fer...

Let M be a complete metric ANR-space such that for any metric compactum K the function space C(K,M) contains a dense set of Bing (resp., Krasinkiewicz) maps. It is shown that M has the following property: If f : X → Y is a perfect surjection between metric spaces, then C(X,M) with the source limitation topology contains a dense Gδ-subset of maps g such that all restrictions g|f(y), y ∈ Y , are ...

In-vitro microbicidal activity of the methanol extract of Origanum majorana L. was tested against seven fungi (Fusarium solani, Candida albicans, Aspergillus niger, A. parasiticus, Rhizopus oryzae, Rhizoctonia otyzae-sativae and Altemaria brassicicola) and six bacteria (Bacillus subtilis, B. megaterium, Escherichia coil, Proteus vulgaris, Pseudomonas aeruginosa and Staphylococcus aureus). The m...

With increasing demand in the field of herbal medicines and cosmetics, it has become necessary and pertinent to probe into the area of systematic knowledge about herbal drugs. There is a need for the application of this knowledge in authentification, detailed study and practical utilization of crude drugs. The present paper deals with the taxonomy, anatomy, powder study pertaining to organolept...

results analysis of the essential oil revealed the presence of pulegone (68.59%) piperitone (7.8%), piperitenone (7.8%), 1, 8-cineole (1.3%), and carvacrol (1.6%) as the major components. the results showed a significant activity against mdr a. baumannii with inhibition zones and minimal inhibitory concentration values in the ranges of 7-15 mm and 20-35 µl/ml respectively. conclusions this inve...

background and purpose: during recent years, nitric oxide (no) has been considered as a molecule involved in migraine headaches. this free radical involves in initiation of migraine headaches via no/cgmp signaling pathway and vascular relaxation specially big intracranial arteries. therefore, we studied the effects of aqueous extract of origanum vulgare and melilotus officinalis prescribed in m...