This is a report of an unusual case, where the patient used clitoral and/or vaginal masturbation and orgasm for treatment of migraine attack. While the non drug treatment was effective, she subsequently developed depression. The orgasm from masturbation, resulting in the rush of endorphins, probably relieved the migraine. However, as demonstrated in our patient, the patient also had sexual aver...

Biological differences in male and female sexuality are obvious in the behavioral domain, but the central mechanisms that might explain these behavioral gender differences remain unclear. In this study, we merged two earlier positron emission tomography data sets to enable systematic comparison of the brain responses in heterosexual men and women during sexual tactile genital (penile and clitor...

The paraventricular nucleus (PVN) of the hypothalamus, which is considered to be a centre for autonomic regulation, has been shown to exhibit physiological and functional sex differences. It is involved in numerous functions, from stress to the appetite, body energy balance, blood pressure, heart rate and sexual activity, including penile erection [1], and is characterised by a very complex arc...

Frotteurism or Frottage is defined by Solomon and Patch (1971) as "sexual pleasure obtained by rubbing or pressing against the object, usually fully clothed woman. It commonly takes place in subways and other crowded situations and may pass unnoticed by the victim. Frotteurs are perverts only if this is the sole mode of obtaining orgasm. Little is known of its psychopathology, but it is thought...