This paper explores the use of self-organizing maps as a mechanism for performing unsupervised learning for signal classification. Approaches using unsupervised learning have a key advantage over traditional approaches that utilize neural networks and support vector machines because they do not require a training phase. We develop signal classifiers using self-organizing maps and explore their ...

Cell polarization is an integral part of many unrelated bacterial processes. How intrinsic cell polarization is achieved is poorly understood. Here, we provide evidence that Caulobacter crescentus uses a multimeric pole-organizing factor (PopZ) that serves as a hub to concurrently achieve several polarizing functions. During chromosome segregation, polar PopZ captures the ParB•ori complex and t...

In this paper, we assume that word co-occurrence statistics can be used to extract meaningful features, exhibiting syntactic and semantic behavior, from text data. Independent component analysis (ICA), an unsupervised statistical method, is applied to word usage statistics, calculated from a natural language corpora, to extract a number of features. With a self-organizing map (SOM), we will dem...

Noncentrosomal microtubules play an important role in polarizing differentiated cells, but little is known about how these microtubules are organized. Here we identify the spectraplakin, Short stop (Shot), as the cortical anchor for noncentrosomal microtubule organizing centers (ncMTOCs) in the Drosophila oocyte. Shot interacts with the cortex through its actin-binding domain and recruits the m...

We have developed an experimental system called PicSOM for retrieving images similar to a given set of reference images in large unannotated image databases. The technique is based on a hierarchical variant of the Self-Organizing Map (SOM) called the Tree Structured Self-Organizing Map (TS-SOM). Given a set of reference images, PicSOM is able to retrieve another set of images which are most sim...

Cell polarization is an integral part of many unrelated bacterial processes. How intrinsic cell polarization is achieved is poorly understood. Here, we provide evidence that Caulobacter crescentus uses a multimeric pole-organizing factor (PopZ) that serves as a hub to concurrently achieve several polarizing functions. During chromosome segregation, polar PopZ captures the ParB*ori complex and t...

Geocast mechanisms allow a sender to transmit network packets to receivers residing at a certain geographical region. Geocast forms the basis for a number of location-based services, such as announcement services, advertisement services or friend-finders. In this paper, we introduce the notion of semantic geocast, where a target area is specified by its meaning. A sender can broadcast messages ...

1. Department of IT, RKGIT Ghaziabad (U.P.) 2. Department of MCA, RKGIT Ghaziabad (U.P.) Abstract: This paper evaluates a self-organizing routing protocol for Ad Hoc network, called the Neuron Routing Algorithm (NEURAL). NEURAL has been designed taking into account the learning and self-organizing abilities of the brain. More precisely, it was inspired by the synapses process between neurons, w...

Abnormal development of multiciliated cells is a hallmark of a variety of human conditions associated with chronic airway diseases, hydrocephalus and infertility. Multiciliogenesis requires both activation of a specialized transcriptional program and assembly of cytoplasmic structures for large-scale centriole amplification that generates basal bodies. It remains unclear, however, what mechanis...

Cell-cell recognition guides the assembly of the vertebrate brain during development. δ-Protocadherins comprise a family of neural adhesion molecules that are differentially expressed and have been implicated in a range of neurodevelopmental disorders. Here we show that the expression of δ-protocadherins partitions the zebrafish optic tectum into radial columns of neurons. Using in vivo two-pho...