C–H Functionalization has the potential to become a paradigmshifting strategy for organic synthesis. Over the last decade, the field has experienced explosive growth and a large variety of new C–H functionalization methodologies have been developed. In particular, regioselective functionalization of sp2 C–H bonds has become a broadly flexible approach for the synthesis of complex aromatic carbo...

Conducting organic syntheses in microfluidic chips allows studying and optimising chemical reactions at minimal time-scales and resource consumption. Herein, we describe a multi-channel microdroplet chip, which allows fast and directed dispensing of reactants into individual droplets in a segmented flow. This gives access to study the reaction progress in situ via surface-enhanced Raman spectro...

This review describes the preparation, structural properties and the use of bisallenes in organic synthesis for the first time. All classes of compounds containing at least two allene moieties are considered, starting from simple conjugated bisallenes and ending with allenes in which the two cumulenic units are connected by complex polycyclic ring systems, heteroatoms and/or heteroatom-containi...

The design and implementation of cascade reactions is a challenging facet of organic chemistry, yet one that can impart striking novelty, elegance, and efficiency to synthetic strategies. The application of cascade reactions to natural products synthesis represents a particularly demanding task, but the results can be both stunning and instructive. This Review highlights selected examples of ca...

The absolute configuration of small crystallizable molecules can be determined with anomalous X-ray diffraction as shown by Bijvoet in 1951. For the majority of compounds that can neither be crystallized nor easily be converted into crystallizable derivatives, stereocontrolled organic synthesis is still required to establish their absolute configuration. In this contribution, a new fundamental ...

Ehsan Noroozizadeh was born in Dezful/Khoozestan, Iran. He received his B.S. in Pure Chemistry (2011) and M.S. in Organic Chemistry (2013) from Bu-Ali Sina University, Iran. He is currently working towards his Ph.D. under the supervision of Professor Mohammad Ali Zolfigol. His research interest is catalysis, including the application of homogeneous and heterogeneous catalysis in organic synthesis.

Mahmoud Zarei was born in Hamedan, Iran in1986. He received his B.Sc. in Pure Chemistry (2010) from Islamic Azad University Arak and M.Sc. in Organic Chemistry (2013) at Bu-Ali Sina University, Iran. He is currently working towards his Ph.D. under the supervision of Professor Mohammad Ali Zolfigol. His research interest is catalysis, including the application of homogeneous and heterogeneous ca...

Organic carbamates represent an important class of compounds showing various interesting properties. They find wide utility in various areas as pharmaceuticals, agrochemicals (pesticides, herbicides, insecticides, fungicides etc.), intermediates in organic synthesis, protection of amino group in peptide chemistry, and as linker in combinatorial chemistry etc. Classical synthesis of carbamates i...