Body CT scans are routinely performed using tube-current-modulation (TCM) technology. There is notable variability across CT manufacturers in terms of how TCM technology is implemented. Some manufacturers aim to provide uniform image noise across body regions and patient sizes, whereas others aim to provide lower noise for smaller patients. The purpose of this study was to conduct a theoretical...

introduction: nowadays ionizing radiation has a considerable contribution in medical diagnostic and treatment. using ionizing radiation is increasing rapidly, so biological effects of ionizing radiation should be considered more. x-rays in the range of diagnostic radiology have hazardous effects and risks that are defined as random effects. these effects obey the lnt hypothesis that occur at lo...

inflammatory bowel diseases (ibd) were systemic disorders involving many organ systems. besides intestinal manifestations, extra intestinal manifestations (eims) including neurologic complications have been reported among 6%-40% of ibd patients. ulcerative colitis (uc) was a subtype of ibd only affecting the colonic mucosa and sub mucosa. although the eims of uc could affect any organ system, c...

BACKGROUND Patients with adolescent idiopathic scoliosis (AIS) frequently receive x-ray imaging at diagnosis and subsequent follow monitoring. The ionizing radiation exposure has accumulated through their development stage and the effect of radiation to this young vulnerable group of patients is uncertain. To achieve the ALARA (as low as reasonably achievable) concept of radiation dose in medic...

The aim of this study was to investigate the organ doses of patients undergoing computed tomography (CT) examination using the wide bore General Electric (GE) “Light Speed RT” unit. The head, chest and pelvic regions of the Rando-phantom were scanned with 120 kV, 200 mA, and 2.5 mm slice thickness for helical and axial modes. Thermoluminescent Dosimeter (TLD) pairs were used for the dosimetry o...

BACKGROUND AND OBJECTIVES High-dose melphalan and autologous stem cell transplantation is currently the treatment of choice for selected patients with AL amyloidosis; however, new treatments are needed for patients who are ineligible for or relapse after this procedure. Bortezomib is a proteasome inhibitor with proven activity in multiple myeloma, and the addition of dexamethasone results in su...