As part of a screening program aimed at the discovery of new lead compounds for the treatment of oral diseases, probiotic Bacillus megaterium isolated from fish gut was studied for its anticaries activity. Our objective is to enumerate the antibacterial effect of Bacillus megaterium against the dental caries causing micro organism Streptococcus mutans. Agar well diffusion to determine Zone of i...

Cinnamon has been used for neuralgia on the knees and waist, and it is shown to have a wide antibacterial spectrum in both Gram-positive bacteria and Gram-negative bacteria. In this study, glucosyltransferase adhesive ability, acid-production suppression effect, and antibacterial activity were measured to identify the anti-caries effect of cinnamon extract. It was shown that cinnamon extract ef...

Bakuchiol was isolated from the seeds of Psoralea corylifolia, a tree native to China with various uses in traditional medicine, followed by extraction with ether and column chromatography combined with silica gel and octyldecyl silane. In this study, the antimicrobial activities of bakuchiol against some oral microorganisms were evaluated in vitro. The cell growth of Streptococcus mutans was i...

The influence of Streptococcus mitis BMS biosurfactants on the adhesion of eight pioneer and four cariogenic oral bacterial strains was, for a first screening, examined in a microtiter plate assay. The adhesion to pellicle-coated wells of three cariogenic strains was inhibited >70% by the biosurfactants, while only one pioneer strain showed >70% reduction. The reduction for the other strains di...

Dental implants play an important role in restorative dentistry. However, the long term implant’s stability is subject on the integration between fixtures and the surrounding tissues. Microbia presented in the oral cavity seems to have a substantial impact on biofilm formation on newly placed implants (1). The natural flora of the mouth is composed of black-pigmented anaerobic bacteria includin...

Streptococcus mutans is the major pathogen of dental caries and occasionally causes infective endocarditis. Here we report the complete genome sequence of serotype k S. mutans strain LJ23, which was recently isolated from the oral cavity of a Japanese patient.

Oral bacteria play an important role in body homeostasis and the bacterial genus Streptococcus is the dominant microflora commonly found in oral bacterial community. Their ability to establish biofilm lifestyle in the oral cavity by outcompeting other bacteria has been attributed to the production of bacteriocin along with other strategies. The goal of the present study was to isolate and ident...

The ability of Streptococcus strains to adhere to the tooth surface in vitro was investigated. Polished enamel slabs, with and without acquired pellicles, were incubated with buffer suspensions of oral streptococci, and attached bacteria were counted under a microscope using incident light. Low numbers of bacteria adhered to uncoated enamel; the presence of an acquired pellicle significantly en...