introduction: granular cell tumors (gcts) are rare and mostly benign soft tissue tumors. though they have been reported in all parts of body, they are generally located in the head and neck region, especially on the tongue. some malign forms exist, but these have been rarely reported. granular cell tumors have a neural origin and, in immunohistochemical evaluations, they express s-100 and neuro...

Aim: To determine the Frequency and Pattern of Presentation Oral Squamous Cell Carcinoma its Predisposing Factors in Patients Presented to Nishtar Institute Dentistry. Study design: Cross sectional study. Place Duration Study: was conducted from Aug 2021 Jan 2022 at Methodology: A total 100 patients were included. aged between18-80 years males females included whom presented with oral squamous ...

Cancer-associated fibroblasts are amongst the key tumor microenvironment components that determine invasion, progression, and resistance to cancer therapeutics. Histologically normal mucosa adjacent oral squamous cell carcinoma has been shown harbor cancer-associated which aid in loco-regional recurrence of lesion. Read more at JCTRes.com

OBJECTIVES Glutathione S-transferase (GST) A1 catalyses the activated heterocyclic aromatic a mine carcinogenN-acetoxy-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OAc-PhIP). This case-control study was carried out to examine whether the genetic polymorphism of GSTA1 is associated with the risk oforal squamous cell carcinoma among Japanese people in relation to their smoking status. MET...

The aim of the study is to determine the levels of E-cadherin, vimentin expression in tumor tissues from patients with oral squamous cell carcinoma (OSCC), and the relationship between the expression of E-cadherin, vimentin and epithelial-mesenchymal transition, in order to explore its values for predicting the invasion and metastasis of oral squamous cell carcinoma, short survival of patients ...

Background: The most frequently mutated tumor suppressor gene found in human cancer is p53. In a normal situation, p53 is activated upon the induction of DNA damage to either arrest the cell cycle or to induce apoptosis. However, when mutated, p53 is no longer able to properly accomplish these functions. The aim of this study was to investigate the expression of p53 gene in cases of skin cancer...

Oral squamous cell carcinoma is the most common malignant epithelial neoplasm affecting the oral cavity. This article overviews the essential points of oral squamous cell carcinoma, highlighting its risk and genomic factors, the potential malignant disorders and the therapeutic approaches. It also emphasizes the importance of the early diagnosis.

background: detection of cancer at an early stage is of utmost importance to decrease the morbidity and mortality of the disease. apart from the conventional biopsy, non‑invasive methods like analysis of serum and saliva may provide cost‑effective approach for screening a large population. tumor markers are a major part of secondary prevention and thus, the detection of malignancies. the aim of...