Pain is a symptom shared by an incredible number of diseases. It is also one of the primary conditions that prompt individuals to seek medical treatment. Head and neck squamous cell carcinoma (HNSCC) corresponds to a heterogeneous disease that may arise from many distinct structures of a large, highly complex, and intricate region. HNSCC affects a great number of patients worldwide and is direc...

The aim of this study was to develop a new pain management method called facilitated tucking by parents (FTP) to alleviate procedural pain in preterm infants in the Neonatal Intensive Care Unit (NICU). In two randomized controlled crossover trials, the effectiveness of FTP was compared to a non-pharmacological evidence-based practice (oral glucose), a pharmacological method (intravenous oxycodo...

Background: Pemphigus vulgaris is a rare autoimmune disorder characterized by cutaneous and mucosal blistering. Surprisingly, the management of oral lesions has been detailed only infrequently. As current topical therapies for oral lesions are of limited efficacy, application of calcineurin inhibitors is considered to be a potential option. The aim of this essay was to investigate the efficacy ...

BACKGROUND The utilization of oral health services in children remains at a relatively low level in China. However, little is known about the utilization patterns and related factors. The objective of this study was to explore the patterns of oral health service utilization and to determine the related factors among preschool children in Beijing, China, based on the Andersen behavioral model. ...

OBJECTIVE We prospectively investigated the efficacy of opioid rotation from oral morphine to oral oxycodone in cancer patients who had difficulty in continuing oral morphine treatment because of inadequate analgesia and/or intolerable side effects. METHODS Twenty-seven patients were enrolled and 25 were evaluated. The rate of patients who achieved adequate pain control, which provided an ind...

Background Third molar extraction is associated with considerable pain and discomfort, which is mostly managed with oral analgesic medication. We assessed the analgesic effect of benzydamine hydrochloride, a topical analgesic oral rinse, for controlling postoperative pain following third molar extraction. Methods A randomized controlled trial was conducted in 40 patients divided into two grou...

PURPOSE To assess 1) patient satisfaction of a mucoadhesive biopatch with citrus essential oil and 2) the change in pain severity and the oral health-related quality of life in patients with recurrent aphthous stomatitis. PATIENTS AND METHODS Thirty-seven patients with recurrent aphthous stomatitis participated in the study. Baseline records of personal data, ulcer assessment, visual analog s...

background: mucositis is an important adverse effect of cancer treatment. the aim of this study was to investigate the effect of ice cubes on oral mucositis following head and neck radiotherapy. materials and methods: a randomized controlled trial was conducted on 40 head and neck cancer patients who underwent radiotherapy. the patients were randomly divided into two experimental and control gr...

Objective: To conduct a systematic review and meta-analysis on the efficacy of oral non-steroidal anti-inflammatory drugs for rotator cuff tendinopathy. Design: Systematic review. Method: A literature search was conducted in 4 databases for randomized controlled trials published until 05/2013, comparing the efficacy of oral anti-inflammatory drugs to any other intervention. Studies characterist...