malignant melanoma is a potentially aggressive tumor of melanocytic origin. primary oral malignant melanoma is a rare neoplasm, accounting for 0.5% of all oral malignancies. the present case occurred in a 60‑year‑old female patient, as a pedunculated growth involving the palate and alveolar ridge and histologically showing a desmoplastic differentiation. the article discusses the distinct clini...

Introdouction: Cone-beam computed tomography (CBCT) scanning is a technological innovation developed in recent years with potential use in oral surgery and many other dental procedures. The aim of this study is to determine the maxillary sinus mucosal thickening in the maxillary premolar-molar area using the CBCT technique. Materials and methods: In this retrospective study, a total of 105 c...

lichen planus is a chronic inflammatory mucocutaneous disease. mucosal lesions are classified into six clinical forms and there is malignant potential for two forms of olp; therefore, follow-up should be considered. there are many un-established etiological factors for olp and some different treatment modalities are based on etiology. the aims of current olp therapy are to eliminate mucosal ery...

The aim of this article is to review literature data about the prevalence of oral mucosal lesions in children in different parts of the world.A total of 16 articles on the prevalence of oral mucosal lesions in children were selected. The lesions were divided into these categories: candida infection, herpes simplex, aphthae, geographic tongue, injuries, which are the most common oral lesions see...

OBJECTIVE To explore an association between oral mucosal alterations and type 2 Diabetes mellitus. METHODS This study was conducted at Baqai Institute of Diabetology and Endocrinology and Baqai Medical University from September 2010 to September 2012. A total of 800 individuals' 395 type 2 diabetes mellitus patients and 405 healthy individuals were enrolled in this study. An oral clinical exa...

Despite the fact that the majority of human pathogens are transmitted across mucosal surfaces, including the oral mucosae, oral immunity is poorly understood. Furthermore, because the normal flora of the oral cavity is vast and significantly diverse, host immunity must balance a complex system of tolerance and pathogen recognition. Due to the rapid recognition and response to pathogens, the inn...

Immunohistochemical demonstration of tumor-associated markers may be valuable as an adjunct to conventional histology for determination of malignancy development in oral mucosal diseases. Accordingly, the present study determined the distribution of some important tumor markers such as heat shock proteins (HSP), fibroblast growth factors (FGF) and transferrin receptors (TF-R) in 22 samples ...

BACKGROUND The purpose of this clinical study was to assess the prevalence of acidic oral mucosal lesions and periodontal conditions in patients suffering from erosive esophageal reflux disease (ERD) compared with non erosive esophageal reflux disease (NERD) patients, both treated with long term proton pump inhibitors (PPI). METHODS Seventy-one patients with diagnosed GERD were studied: i.e. ...

Diseases and symptoms of mouth mucosa are prevalent in particular in the ageing populations. For example, a nationwide representative examination in the US revealed approximately 28% prevalence of all oral mucosal lesions in subjects 17 years of age and older with distinct differences between age groups and whether or not the subject smoked [27]. There are no comprehensive epidemiological data ...