218 Indian Dermatology Online Journal | Volume 8 | Issue 3 | May‐June 2017 Many viruses including HHV6 and HHV7 have been proposed as causative agents for pityriasis rosea, although there is no conclusive evidence. Here, we presented a case of pityriasis rosea coexisting with oral HSV1 infection. Our case is unique because purpuric pityriasis rosea has not been associated with HSV1 previously. ...

weeks, pneumatosis and pneumoperitoneum had completely resolved. We suggest that a smouldering gastrointestinal CMV disease proven by biopsy 8 weeks before and incompletely suppressed by oral acyclovir was the cause of pneumatosis in our patient. Leukocyte CMV immediate early antigen remained negative, but this is known in an isolated gastrointestinal CMV disease, even if no specific suppressiv...

The prevalence and accelerated course of recurrent hepatitis C infection after liver transplantation is associated with significant morbidity and mortality. Use of dual therapy with interferon/ribavirin or triple therapy with first-generation NS3/4 protease inhibitors for the treatment of hepatitis C in cirrhotic and post-transplant patients has yielded only modest sustained virologic response ...

OBJECTIVE Erythema multiforme (EM) is an immune-mediated condition characterized by the appearance of target-like lesions on the skin and often accompanied by erosions or bullae involving the oral, genital, and/or ocular mucosae. 70% of recurrent EM cases are associated with HSV reactivation and it is labelled as herpes-associated erythema multiforme (HAE M). Recurrences are seen in approximate...

conclusions the changes of treg and th17 cells and their associated cytokines were related to virological and biochemical responses. results in complete and partial-responders, treg cells frequencies and il-10, tgf-β1, il-23 levels were all decreased significantly after na therapy, while th17 cells and the il-17 levels were increased slightly. treg/th17 ratio was only dramatically declined in c...

introduction: oral mucositis is considered a severe complication in cancer patients receiving radiotherapy or chemotherapy for head and neck cancer. the aim of this review study was to assess the effect of low level laser therapy for prevention and management of oral mucositis in cancer patients. methods: the electronic databases searched included pubmed, isi web of knowledge and google scholar...

The TRANSPEG study was a prospective study to assess the efficacy of antiviral therapy in patients with a recurrent hepatitis C virus (HCV) after liver transplantation. The influence of regulatory T-cells (Tregs) on the response to antiviral therapy was analyzed. Patients were considered as a function of their sustained virological response (SVR) at 18 months after treatment initiation. A trans...

Currently available antiviral therapies specifically target viral replication by blocking reverse transcription with orally given nucleos(t)ide analogues and are able to specifically suppress viral replication. The unique replication strategy of hepatitis B virus (HBV), however, allows long-term persistence of the viral genome within infected hepatocytes in spite of successful therapy. Thus, an...

We report our findings for a patient with orbital apex syndrome associated with herpes zoster ophthalmicus. Our patient was initially admitted to a neighborhood hospital because of nausea and loss of appetite of 10 days' duration. The day after hospitalization, she developed skin vesicles along the first division of the trigeminal nerve, with severe lid swelling and conjunctival injection. On s...

The persistence of latently infected resting CD4+ T cells has been clearly demonstrated in human immunodeficiency virus (HIV)-infected individuals receiving effective antiviral therapy. However, estimates of the half-life of this viral reservoir have been quite divergent. We demonstrate clear evidence for decay of this HIV reservoir in patients who initiated antiviral therapy early in infection...