PURPOSE To report the cross-sectional structure of the retina and choroid in eyes with adult-onset vitelliform macular dystrophy as obtained by optical coherence tomography (OCT). METHODS Seven patients with adult-onset vitelliform macular dystrophy and one patient with Best disease were examined by fundoscopy, fluorescein and indocyanine green angiography and OCT. Three patients underwent al...

PURPOSE To evaluate the utility of anterior segment optical coherence tomography (AS-OCT) assessment in the pre- and postsurgical management of full-thickness corneal grafts. METHODS Seventy eyes of 58 patients who had penetrating keratoplasty were included in the study. High resolution AS-OCT scans of the cornea and the anterior segment were performed before and after transplantation in 17 e...

Examination of brain functions in small animal models may help improve the diagnosis and treatment of neurological conditions. Transcranial imaging of small rodents' brains poses a major challenge for optical microscopy. Another challenge is to reduce the measurement time. We describe methods and algorithms for three-dimensional assessment of blood flow in the brains of small animals, through t...

We report a new approach in optical coherence tomography (OCT) termed full-field Fourier-domain OCT (3F-OCT). A three-dimensional image of a sample is obtained by digital reconstruction of a three-dimensional data cube, acquired using a Fourier holography recording system illuminated with a swept-source. This paper presents theoretical and experimental study of the signal-to-noise ratio of the ...

purpose: to assess foveal thickness by spectral-domain optical coherence tomography (sd-oct) during acute anterior uveitis (aau) in hla–b27 patients. methods : foveal thickness was measured at baseline and after clinical resolution of the uveitis. data of the affected eyes of 11 patients were compared to those of a fellow, healthy eyes and to those of counterpart volunteers. results: at basel...

High-speed, high-resolution optical coherence tomography (OCT) imaging of the human retina is demonstrated using a frequency-swept laser at 850 nm. A compact external cavity semiconductor laser design, optimized for swept-source ophthalmic OCT, is described. The laser enables an effective 16 kHz sweep rate with >10 mm coherence length and a tuning range of approximately 35 nm full width at half...

For the first time, we present co-registered autofluorescence imaging and optical coherence tomography (AF/OCT) of excised human palatine tonsils to evaluate the capabilities of OCT to visualize tonsil tissue components. Despite limited penetration depth, OCT can provide detailed structural information about tonsil tissue with much higher resolution than that of computed tomography, magnetic re...

The vitreous body is bounded posteriorly by the retina and is adherent to it. Abnormalities in the adhesion between the vitreous and the macula, or vitreoretinal interface, are involved in the pathogenesis of several macular conditions. Optical coherence tomography is a noninvasive in vivo ophthalmic imaging technique, which allows for a better understanding and improved diagnosis of disease pr...

We review the current state of research in endoscopic optical coherence tomography (OCT). We first survey the range of available endoscopic optical imaging techniques. We then discuss the various OCT-based endoscopic methods that have thus far been developed. We compare the different endoscopic OCT methods in terms of their scan performance. Next, we examine the application range of endoscopic ...