STUDY OBJECTIVE To describe temporal and geographical variations in mortality from acute reactions to opiates or cocaine and the demographic and toxicological characteristics of persons who died from these in major Spanish cities between 1983 and 1991. DESIGN Descriptive study. Data were obtained retrospectively from pathologists' reports. SETTING Cities of Madrid, Barcelona, Valencia, Sevi...

The historical patterns of opiate use show that sources and methods of access greatly influence who is at risk. Today, there is evidence that an enormous increase in the availability of prescription opiates is fuelling a rise in addiction nationally, drawing in new initiates to these drugs and changing the geography of opiate overdoses. Recent efforts at supply-based reductions in prescription ...

Objective: Substance use disorder (SUD) continue to be a problem for the whole world in first quarter of twenty-first century. The leading centres treatment SUD our country are Alcohol-Drug Addiction Research Treatment and Training Centres (AMATEM). In this study, we aimed examine 2017 data AMATEM outpatients province. Material Methods: study was conducted as retrospective applications between ...

That the brain stem, particularly the reticular core, is involved in the receipt and processing of sensory information of wide variety, including pain, is well appreciated [e.g., 26,104,105,230]. While nociception and ~tinociception have long been poorly understood, the recent past has seen significant advances made in our appreciation and understanding of the involvement of brain stem areas in...