PURPOSE To analyze the difference between measurements of Schirmer test I (STI) and basal Schirmer test (STB) with open and closed eyes. METHODS Sixty eyes of 30 normal volunteers, 12 males and 18 females aged 28 +/- 9 years were recruited for the study. All ST were carried out in a closed environment with the absence of airflow (humidity 60 +/- 2.34% and temperature 20.72 +/- 1.52 degrees C)...

Dry eye is a common disorder in routine ophthalmological practice, and a better understanding of the complex pathophysiology is leading to improved treatment. Thealoz Duo(®) is a novel artificial tear preparation containing two active ingredients: Trehalose, a naturally occurring disaccharide with anhydrobiotic functions in many organisms, and hyaluronate, a widely distributed anionic glycosami...

AIMS To determine the incidence, natural course, and severity of dry eye occurring or worsening after haematopoietic stem cell transplantation (SCT). METHODS At a tertiary care hospital, 53 patients undergoing allogeneic or autologous SCT followed by at least 180 days of follow up were studied prospectively. Examination included grading of symptoms of dry eye, evaluation of ocular surface, te...

BACKGROUND Dry eye disease (DED) is multifactorial, affecting 5-34 % of the global adult population and reducing quality of life. The artificial tears or lubricants are the therapy most used for the treatment of DED, due to their low side effect profile, which attempt to modify the properties of the tear film. The aim of the present study was to evaluate the clinical efficacy of a fixed combina...

Dry eye is often an under diagnosed condition of the that can cause discomfort, burning sensation and blurred vision. These symptoms are related to alterations in layers tear film, insufficient production or excessive evaporation film. The primary aim this study diagnose find out incidence dry patients presenting with ocular irritation. A total number 225 both sexes aged between 20 80 years com...

PURPOSE To investigate the association of dry eye disease with sleep quality. METHODS In 2011, a cross-sectional survey was conducted among all the employees, mainly young and middle-aged Japanese office workers, who used visual display technology, at a company in Osaka, Japan (N=672; age range =26-64 years). The participants were classified according to the Japanese dry eye diagnosis criteri...

PURPOSE To evaluate the effectiveness of topical cyclosporine A 0.05% for treatment of mustard gas-induced ocular surface disorders with special attention to conjunctival goblet cell density in patients with severe dry eye. METHODS This prospective clinical study included 20 eyes of 20 patients previously exposed to mustard gas with dry eye syndrome unresponsive to artificial tears. Before an...

Purpose. Adult active smoking is a risk factor for dry eye. We hypothesize that passive smoking in children can also produce the same effects. Methods. We included 112 school children presenting with eye discomfort. Assessment of eye dryness and its severity levels depending on symptoms of dry eye, visual symptoms, tear breakup time (TBUT), Schirmer-1 test, and corneal fluorescein staining were...

Our aim is to investigate the presence of dry eye in fibromyalgia (FM) patients with using a self-reported questionnaire and objective tests. This study included 20 who were newly diagnosed FM healthy controls. Both groups evaluated ocular surface disease scale (OSDI), non-anesthetized Schirmer-I test, meibography, tear meniscus assessment, fluorescein break time (FBUT), non-invasive (NITBUT) c...

OBJECTIVE To assess the effectiveness of sodium hyaluronate Eye Gel in Dry Eye Disease (DED) patients Methods: A Multi-center, Open-label, Uncontrolled clinical trial was conducted in different centers of Pakistan. Ten ophthalmologists conducted this study in which 250 diagnosed patients with dry eye disease were enrolled after obtaining a written informed consent. Ten patients were dropped out...