OBJECTIVE This study is to identify the reliability of osteonecrosis of the femoral head (ONFH) modeling established by MRI guided argon helium cryotherapy system in beagles. METHODS A total of 15 beagles were used to establish the ONFH model. The left femoral heads of the beagles received two cycles of argon helium freezing-thawing under MRI guidance and were considered as experimental group...

The purpose of this study is to evaluate the survivorship and risk factors for radiographic progression and conversion to total hip arthroplasty (THA) after porous tantalum implant surgery in the treatment of osteonecrosis of the femoral head (ONFH). The study comprised 90 ONFH patients (104 consecutive hips) who were treated with a porous tantalum implant combined with bone grafting between Ju...

The study aimed to evaluate the association between MMP gene superfamily and alcohol-induced osteonecrosis of femoral head (alcohol-induced ONFH) risk given its high prevalence, poor therapeutic effect, and serious clinical prognosis. 308 subjects (mean age, 49.47 years; males, 64.0%) who participated in our control group and 300 alcohol-induced ONFH patients (mean age, 43.29 years; males, 99.7...

This study aims to evaluate the clinical efficacy of core decompression with bone grafting combined with perifemoral arterial infusion (CDBG-AI) in treating stage I-II osteonecrosis of the femoral head (ONFH). A total of 40 patients (40-70 years old) with stage I-II ONFH were enrolled. Initially, these patients underwent core decompression plus implantation of allogeneic bone and CaSO4 particle...

Free vascularised fibular grafting has been reported to be successful for adult patients with osteonecrosis of the femoral head (ONFH). However, its benefit in teenage patients with post-traumatic ONFH has not been determined. We evaluated the effectiveness of free vascularised fibular grafting in the treatment of this condition in children and adolescents. We retrospectively analysed 28 hips i...

The aim of this study was to evaluate the efficacy and clinical application of iliac bone flaps pedicled with sartorius muscular fascia around superficial circumflex iliac vessels for the treatment of Association for Research on Osseous Circulation (ARCO) stage II-III osteonecrosis of the femoral head (ONFH) in young adults. In total, 35 patients with ONFH at ARCO stage II-III were treated with...

Objective Based on Traditional Chinese Medicine (TCM) classics, this paper, by searching the literature treatment of femoral head necrosis with TCM, aims to explain essence theory “blood stasis removal - regeneration bone fusion”, analyze development modern medicine in osteonecrosis (ONFH), and provide new ideas for ONFH integrated traditional western medicine. Methods CNKI, PubMed, Wanfang VIP...

Background Adult-onset Still’s disease (AOSD) is a rare systemic autoinflammatory disease, characterized by symptoms such as spiking fever, arthralgia, sore throat, and skin rashes. The detailed pathogenesis of AOSD not yet understood, hence the management often involves use corticosteroids. Among glucocorticoid-associated complications, osteonecrosis femoral head (ONFH) immediately life threat...