What are the symptoms? The most common symptom is joint pain. It is usually in the hands, feet, hips, knees, or spine. In the hand, it often affects the joint at the base of the thumb. In the foot, it is usually at the base of the big toe. The pain can be worse after periods of rest, like when you first get up in the morning or when you get up out of a chair. Osteoarthritis can also limit movem...