Perception of temporal synchrony between one's own action and the sensory feedback of that action is quite flexible. We examined whether sensorimotor temporal recalibration (TR) involves central or motor-specific components by concurrently exposing the left and right hands to different lags. The experiment was composed of a pre-test, an adaptation phase, and a post-test. During the adaptation p...

OBJECTIVES Systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) can both present with an erosive arthritis with the small joints of the hands affected. Therefore a serological marker would be useful to distinguish between these two diseases at onset. In this study anti-RA33 antibodies, which are found in patients with SLE and RA, and anti-citrullinated peptide antibodies (anti-CCP),...

1. Introduction In order to learn a new word, children first need to determine what form class the word belongs to, and find an appropriate referent in the situation in which the word is introduced. They then must determine what other instances the word should be (or should not be) generalized to. In doing so, children need to realize that generalization of words are governed by different princ...

OBJECTIVE The most cost-effective dosing regimen for rituximab treatment in RA is currently unknown. The objective of this study is to determine whether low rituximab serum levels are associated with progression of structural damage in RA patients. METHODS Sixty-two RA patients were treated with rituximab in three different centres. Structural damage was assessed on radiographs of hands and f...

When looking forward, it is often useful to explore the past. I would like to begin this address by revisiting recent history, attempting to learn lessons which may help us understand future trends. In 1754, Anthony Henday was dispatched by the Hudson’s Bay Company to seek out new territories and trading partners for the lucrative fur trade. He paddled down the Hayes River and crossed overland ...

This study was carried out to determine the incidence of agenesis of Palmaris longus muscle and the frequency of left handed individuals among the Ijaw ethnic group in Bayelsa State in Nigeria. A check on the incidence of agenesis was carried out on adult males and females on both hands by inspection. The flexor tendon was made prominence by flexing thumb and placing it on the little finger. Th...

To assess the role of subregions of the posterior association cortex in movement control, we recorded movement-related potentials (MRPs) in patients who had lesions centered in the temporal-parietal junction (T-PCx; damaged areas 22, caudal 39, 40, and 42; n = 7), superior parietal cortex (ParCx; damaged areas 5, 7, rostral 39, and 40; n = 5), and posterior association cortex lesions involving ...

OBJECTIVES To document the transition to a totally one-stop (patient seen and treated in one appointment) wide-awake (local anaesthesia only) hand surgery service. DESIGN Retrospective review of 10 year service with detailed analysis of last 1000 cases including process and cost-effectiveness and efficiency analysis. SETTING Purpose-built CQC-certified day-case surgical facility where we ha...