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تعداد نتایج: 2008595  

Journal: :Haematologica 2010
Marvin M van Luijn Martine E D Chamuleau James A Thompson Suzanne Ostrand-Rosenberg Theresia M Westers Yuri Souwer Gert J Ossenkoppele S Marieke van Ham Arjan A van de Loosdrecht

BACKGROUND Disease recurrence in patients with acute myeloid leukemia may be partially explained by the escape of leukemic blasts from CD4(+) T-cell recognition. The current study investigates the role of aberrant HLA class II antigen presentation on leukemic blasts by determining both the clinical and functional impact of the class II-associated invariant chain peptide (CLIP). DESIGN AND MET...

Journal: :The Journal of clinical investigation 1984
J B Marshall L P Kapcala L D Manning A J McCullough

Naturally occurring derivatives of pro-opiomelanocortin (POMC) have been identified in various extra-pituitary sites, including the endocrine and exocrine pancreas. Corticotropin-like intermediate lobe peptide (CLIP = ACTH18-39), a naturally occurring derivative of POMC, has been suggested to be an insulin secretagogue. To determine whether CLIP might also affect the exocrine pancreas, we measu...

Journal: :Protocol Exchange 2018

1997
Nitin Sawhney David Balcom Ian Smith

methodology is needed to integrate and exchange spatial and temporal properties in hyper-media and hypertext. We propose a generic framework to structure and dynamically present a new form of video-and text-based media called hypervideo. We developed a Hypervideo Engine and produced an experimental hypermedia work, HyperCafe, to illustrate the general properties and aesthetic techniques possibl...

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