One in seven types of human cancer is associated with an oncogenic virus infection. Most human tumors have high telomerase activity but very short telomeres, yet the maintenance of these short telomeres is critical to avoid telomere end fusion or senescence and to support active proliferation. Oncogenic viruses have evolved a wide repertoire of strategies to stimulate telomerase functions at th...

Oncogenic viruses are the etiologic agents for a significant proportion of human cancers, but effective therapies and preventative strategies are lacking for the majority of virus-associated cancers. Targeting of virus-induced signal transduction or virus-host protein interactions may offer novel therapeutic strategies for viral cancers. Heat shock protein 90 (Hsp90) is a well-characterized, mu...

background: colorectal cancer is one of the most common malignancies worldwide with more than one million new cases diagnosed each year . the aim of this study is to investigate the prevalence of herpes simplex virus and epstein-barr virus in patients with colorectal carcinomas and polyps in comparison with healthy subjects by using the polymerase chain reaction technique. methods: in this anal...

Negative staining of virions and isolated nucleoids from avian myeloblastosis virus, murine leukemia virus, murine mammary tumor virus, and feline leukemia virus reveals common internal structures. The majority of virions that are penetrated by phosphotungstate show spherical nucleoids with no apparent symmetry. In a small percentage of virions, two distinctive structures are found: (i) single ...

Water can contain pathogenic viruses. Many studies on RNA virus sources have shown that water transmit them. However, there are few reports DNA transmission through water, such as adenovirus, which pose a widespread public health risk. Therefore, this study aimed to show waterborne viral by detecting viruses in pooled human whole blood samples, tap and natural from Mueang District, Phayao Provi...

Ongoing viral research, essential for public health due to evolving viruses, gains significance owing emerging infections such as the SARS-CoV-2 pandemic. Marine and plant alkaloids show promise novel potential pharmacological strategies. In this narrative review, we elucidated of tylophorine lycorine, two naturally occurring plant-derived with a shared benzoindolizidine scaffold, antiviral age...