Although robust age effects on human navigation have been demonstrated, age differences in cue-use is poorly understood. In this study, older and younger adults completed a virtual environment (VE) navigation task. The environment contained cues divided into 2 categories. ’Critical cues’ (CC) were located at decision points, while ’non-critical cues’ (NCC) were located at non-decision points. F...

AIM To investigate possible age-related changes in glycosaminoglycans (GAGs) in the human cornea. The substances today called GAGs were previously referred to as mucopolysaccharides. METHODS Samples of human cornea were taken from 12 younger (age 21 ± 1.2) and 12 older (age 72 ± 1.6) male subjects. Samples were weighed, homogenized, and used for biochemical and molecular analyses. All the qua...

While age-related declines in walking mechanics have been documented, it remains unclear if changes in walking mechanics with age occur as a natural consequence of aging and to what extent these changes are related to a reduction in fitness and physical activity with aging. The study aim was to determine if the walking mechanics of an older (>50) yet highly active population are different from ...

The ability to control encoding and retrieval processing strategically is critical for the efficient use of memory. We examined the ability of younger and older adults to selectively remember words on the basis of their arbitrary point values by using a technique developed by Watkins and Bloom (1999). In the first three experiments, younger subjects recalled more words than did older subjects, ...

OBJECTIVE To evaluate the associations of presbyopia and its correction, particularly monovision optical correction, with vision-targeted health-related quality of life. METHODS The National Eye Institute Refractive Error Quality of Life (NEI-RQL) Instrument was prospectively self-administered by subjects from 6 medical centers in the following age and correction categories: subjects with emm...

Nineteen amino acids were determined in the plasma of young and older individuals by the chromatographic procedure of Moore, Spackman, and Stein (7,8). Of the essential amino acids, valine, methionine, isoleucine, leucine, phenylalanine, and lysine were found to be lower in older subjects. In all, 11 of the 19 amino acids studied showed lower values in these individuals, indicating some differe...

Forty-two cases of bacterial endocarditis with pathologic confirmation are reviewed. Infection was restricted to one or both left-sided valves in 31 cases, right-sided valves in five cases, and valves in both sides of the heart in six cases. In those specimens available for review, underlying valvular disease was identifiable in 24 of 38 cases (63%). The common underlying diseases, in order of ...

INTRODUCTION Physical activity (PA) is important for healthy ageing. Better insight into objectively measured PA levels in older adults is needed, since most previous studies employed self-report measures for PA assessment, which are associated with overestimation of PA. AIM This study aimed to provide insight in objectively measured indoor and outdoor PA of older adults, and in PA difference...