BACKGROUND Two mammalian digitalis-like factors, an ouabain-like compound (OLC) and marinobufagenin (MBG), exhibit specificity to alpha-3 and alpha-1 Na(+),K(+)-ATPase isoforms, respectively. We compared regulation of MBG and OLC by acute NaCl loading in Dahl salt-sensitive (DS) and salt-resistant (DR) rats. METHODS AND RESULTS An intraperitoneal NaCl load (0.8 g/kg) was given to adult male r...

BACKGROUND Digitalis-like sodium pump ligands (SPLs) effect natriuresis via inhibition of renal tubular Na(+),K(+)-ATPase but may induce vasoconstriction. The present study investigated the potential roles of 2 putative endogenous SPLs, an ouabain-like compound (OLC) and an alpha(1) Na(+),K(+)-ATPase inhibitor, marinobufagenin (MBG), in regulating natriuresis and blood pressure (BP) responses t...

This paper delineates an instrumental multi-case study conducted in Taiwan with university faculty. The study explores higher education teachers’ standpoints concerning adoption of online learning community (OLC) as a strategy for continuing professional development (CPD) taking advantage of the technique frequently applied to program planning or decision making analyses on internal effects of ...

Andrews's recent proof of the Mills-Robbins-Rumsey conjectured formula for the number of totally symmetric self-complementary plane partitions is used to derive a new multi-variate constant term identity, reminiscent of, but not implied by, Macdonald's BC,-Dyson identity. The method of proof consists in translating to the language of constant terms an expression of Doran for the desired number ...

The quantum system under periodical modulation is the simplest path to understand nonequilibrium because it can be well described by effective static Floquet Hamiltonian. Under stroboscopic measurement, initial phase usually irrelevant. However, if two uncorrelated parameters are modulated, their relative cannot gauged out so that physics dramatically changed. Here, we simultaneously modulate f...