The aim of this study was to improve the water solubility of raloxifene by complexing it with sulphobutylether-β-cyclodextrin. Inclusion complexation in aqueous solution and solid state was evaluated by the phase solubility diagram, powder X-ray diffractometer, Fourier-transform infrared spectroscopy, nuclear magnetic resonance, scanning electron microscopy, hot stage microscopy and transmissio...

background and objectives: application of garlic oil in food industry can be improved by encapsulation. there is no study about the formation of inclusion complex of garlic oil by beta-cyclodextrin. the aim of the present study is comparison of the antioxidant and antibacterial activities of free and encapsulated garlic oil with beta-cyclodextrin. materials and methods: antioxidant activity was...

Cyclodextrins are capable of forming non-covalent host-guest inclusion complexation with variety of molecules in order to enhance water-solubility and thermal stability of such hydrophobic and volatile molecules. Menthol, an efficient antibacterial and flavour/fragrance agent, is used in various applications like food, pharmacy, cosmetics, however, its low water-solubility and high volatility s...

Considering the potential of nanostructured titanium dioxide layers as drug delivery systems, it is advisable to indicate possibility creating a functional system based on anodic TiO2 for celecoxib an alternative anti-inflammatory and its inclusion complex with β-cyclodextrin. First, optimal composition celecoxib—β-cyclodextrin complexes was synthesized determined. The effectiveness complexatio...

Fexofenadine is a selective histamine H(1) receptor antagonist, used for relief of the symptoms of allergy. However its aqueous solubility is very poor. Solid inclusion complexes of fexofenadine and β-cyclodextrin were prepared at the molar ratios of 1:1 and 1:2 by kneading, and coprecipitation methods to improve its solubility. Characterization of the complexes was performed using infrared spe...

Molecular docking and quantum chemistry calculations were used to establish the molecular model of β-cyclodextrin inclusion complex with five major compounds found in Thai sweet basil (Ocimum basilicum) essential oils, which includes linalool, eugenol, methyl eugenol, estragole, and eucalyptol. The electronic structures and the binding energies of 1:1 inclusion complexes of host:guest ratio for...

Abstract Ozone (O3) has been widely used for the elimination of recalcitrant micropollutants in aqueous environments, due to its strong oxidation ability. However, utilization efficiency O3 is constrained by low solubility and short half-life during treatment process. Herein, an integrated approach, using nanobubble technology micro-environmental chemistry within cyclodextrin inclusion cavities...