Pituitary adrenocorticotrophic hormone (ACTH) and cortisone have already become established as important therapeutic agents in many diseases, and an enormous literature has accumulated since their effect in rheumatoid arthritis was announced by Hench and others (1949). After an initial wave of uncritical enthusiasm, the applications and limitations of these hormones are now being realized, but ...

BACKGROUND Scleritis may be the initial or only presenting feature of systemic, autoimmune, or infectious disorders. Corticosteroids are the mainstay of treatment for immune-mediated scleritis. However, steroids could prove detrimental when used to treat infectious scleritis. Hence, infectious causes of scleritis should be ruled out. FINDINGS A 47-year-old male from central India presented wi...

The human eye, as an organ, can offer critical clues to the presence of systemic disease. This article discusses the various ophthalmologic manifestations of systemic disease that can be evident on examination by an emergency department provider, as well as some findings that can be discerned with specialty consultation. The following topics are reviewed with respect to potential ocular signs a...

Background This study investigated the prevalence for hepatitis A virus (HAV), hepatitis E virus (HEV), herpes simplex virus type 2 (HSV2) and syphilis among homeless in the city of Tehran.   Methods In this cross-sectional study, 596 homeless were recruited in Tehran. A researcher-designed questionnaire was used to study demographic data. Using enzyme-linked immunoassay, and rapid plasma reagi...

Congenital Syphilis in U.S. Infants Born 2020 As of July 29, 2021, a total 2022 cases congenital syphilis were reported to the Centers for Disease Control and Prevention, already surpassin...