PURPOSE To report a case of primary acquired melanosis (PAM) successfully treated with combined topical mitomycin C and interferon-α2b. CASE REPORT A 75-year-old man presented with an extensive unilateral pigmented lesion involving 360° of the bulbar conjunctiva, extending to the fornices and palpebral conjunctiva. Map biopsy confirmed PAM with local atypia. Treatment was initiated with mitom...

Diabetic retinopathy (DR) is a microvascular lesion that occurs as complication of diabetes mellitus. Many studies reveal retinal neurodegeneration early in its pathogenesis, and abnormal function can occur patients without any signs abnormalities. The gut microbiota large, diverse colony microorganisms colonize the human intestine. Studies indicated involved pathophysiological processes DR pla...

Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a severe drug reaction characterized by extensive destruction of the epidermis and mucosal epithelia. The eyes are typically involved in TEN. The precise pathomechanisms involved remain unknown. We present a case of toxic epidermal necrolysis in a healthy 46-yr-old female patient who had inhaled glycophosphate (herbicide) and ...

PURPOSE To report a case of delayed-onset bilateral scleral thinning and calcium deposition following a cosmetic ocular-whitening procedure (I-BRITE(®)). METHODS A 33-year-old male patient with a history of right-sided ptosis repair and left-sided anterior uveitis had previously undergone bilateral I-BRITE treatment for chronic conjunctival hyperemia. Four years after the procedure, the patie...

Acute corneal hydrops is a rare complication caused by a rupture in Descemet’s membrane as a result of progressive corneal thinning, normally due to advanced forms of corneal ectatic disorders.We report a case of unilateral pellucid marginal degeneration (PMD) which presented as acute corneal hydrops in a 56-year-old woman with no history of ocular or systemic disease. J Emmetropia 2014; 5: 43-...

Herpes zoster (HZ) corresponds to the reactivation of varicella zoster virus (VZV). Among adults, the ophthalmic division of the trigeminal nerve is one of the most common sites of involvement. Vasculopathy caused by HZ is associated with significant morbidity and mortality, affecting structures such as the brain, which can lead to stroke. In this review, we analyzed the epidemiological and cli...

Raised intraocular pressure is a frequently encountered complication of uveitis. Intraocular homeostasis, maintained by the impermeable blood-ocular barrier, is important to guarantee optimal visual function. During uveitis breakdown of the blood-ocular barrier occurs, allowing the influx of proteins as well as inflammatory and immunocompetent cells. The combination of action of inflammatory ce...

This retrospective study investigated the role of antivascular endothelial growth factor agents (VEGF), ranibizumab, bevacizumab and pegaptanib sodium in patients with iris neovascularisation (INV), in which 9 eyes received intraocular injections for various ischaemic ocular conditions. Ocular sequelae included recurrence of rubeosis (n=2) and hyphaema (n=2). Systemic complication included one ...

Cytomegalovirus (CMV) retinitis is the commonest ocular complication of AIDS and the prevention of recurrence has been dependent on lifelong maintenance treatment. Recently there has been a dramatic downturn in the number of new cases of CMV retinitis, which has been attributed to the introduction of highly active antiretroviral therapy (HAART) and subsequent improved survival. Whereas paucity ...

Stevens Johnson syndrome has been reported in 0.3% of patients taking Nevirapine as non nucleoside reverse transcriptase inhibitor in the Highly Active AntiRetroviral Therapy within first four to six weeks of treatment. We report one such uncommon case in a young adolescent HIV infected male who developed generalized skin eruptions with mucous membrane involvement of genitalia, oral cavity and ...