نتایج جستجو برای: ocular blood flow

تعداد نتایج: 1139465  

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2000
M Bayerle-Eder M Wolzt E Polska H Langenberger J Pleiner D Teherani G Rainer K Polak H G Eichler L Schmetterer

Carbon dioxide is an important regulator of vascular tone. Glibenclamide, an inhibitor of ATP-sensitive potassium channel (K(ATP)) activation, significantly blunts vasodilation in response to hypercapnic acidosis in animals. We investigated whether glibenclamide also alters the cerebral and ocular vasodilator response to hypercapnia in humans. Ten healthy male subjects were studied in a control...

Journal: :Graefe's Archive for Clinical and Experimental Ophthalmology 2007

Journal: :Investigative ophthalmology & visual science 2003
Gabriele Fuchsjäger-Mayrl Alexandra Luksch Magdalena Malec Elzbieta Polska Michael Wolzt Leopold Schmetterer

PURPOSE There is evidence that the choroid has some autoregulatory capacity in response to changes in ocular perfusion pressure (OPP). The mediators of this response are hitherto unidentified. The hypothesis for the current study was that endothelin (ET)-1 and/or angiotensin (ANF)-II may be involved in choroidal vasoconstriction during an increase in OPP. METHODS To test this hypothesis a ran...

Journal: :Biomechanics and modeling in mechanobiology 2016
Andrea Dziubek Giovanna Guidoboni Alon Harris Anil N Hirani Edmond Rusjan William Thistleton

A computational model for retinal hemodynamics accounting for ocular curvature is presented. The model combines (i) a hierarchical Darcy model for the flow through small arterioles, capillaries and small venules in the retinal tissue, where blood vessels of different size are comprised in different hierarchical levels of a porous medium; and (ii) a one-dimensional network model for the blood fl...

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