BACKGROUND Obstructive sleep apnea syndrome (OSA) is an important cause of morbidity and mortality in adults. AIM To evaluate the diagnostic value of clinical features and oximetric data to screen for obstructive sleep apnea before performing polysomnograpy or respiratory polygraphy. MATERIAL AND METHODS We studied 328 consecutive adult patients referred for snoring or excessive daytime sle...

Whether nasal congestion promotes obstructive sleep apnea is controversial. Therefore, we performed a randomized placebo-controlled cross-over trial on the effects of topical nasal decongestion in patients with obstructive sleep apnea syndrome (OSA) and nasal congestion. Twelve OSA patients with chronic nasal congestion (mean +/- SD age 49.1 +/- 11.1 years, apnea/hypopnea index 32.6 +/- 24.5/h)...

Endothelial activation and inflammation are important mediators of accelerated atherogenesis and consequent increased cardiovascular morbidity in obstructive sleep apnea (OSA). Repetitive episodes of hypoxia/reoxygenation associated with transient cessation of breathing during sleep in OSA resemble ischemia/reperfusion injury and may be the main culprit underlying endothelial dysfunction in OSA...

Background: Obstructive Sleep Apnea (OSA) is the most common sleep breathing disorder. In OSA, interrupted by a blockage of airflow. Objective: This study was aimed to assess updated technique for endoscope-guided coblator tongue base reduction treatment patients with OSA. Patients and Methods: clinical trial included total 12 moderate severe attending at Department Otorhinolaryngology, Facul...

Obstructive sleep apnea (OSA) is associated with numerous comorbid conditions. In many, a causative relationship has either been well established or strongly associated. As the knowledge of sleep-disordered breathing and its consequences continues to grow, so does the list of associated or consequential conditions. This article is part 2 of a 5-part series exploring more recently identified con...

Obstructive sleep apnea (OSA) is a common sleep disorder characterized by repetitive episodes of apnea and hypopnea during sleep. The symptoms include excessive daytime sleepiness, non-refreshing sleep, daytime fatigue, and decreased concentration, which may cause marked impairment in social or occupational functioning. In addition, the patients with OSA were shown to have an increased risk of ...

IN BRIEF Obstructive sleep apnea (OSA) alters glucose metabolism, promotes insulin resistance, and is associated with development of type 2 diabetes. Obesity is a key moderator of the effect of OSA on type 2 diabetes. However, chronic exposure to intermittent hypoxia and other pathophysiological effects of OSA affect glucose metabolism directly, and treatment of OSA can improve glucose homeosta...

BACKGROUND Obese humans are reported to have increased muscle sympathetic nerve activity (MSNA). Obstructive sleep apnea (OSA) may also be accompanied by increased MSNA. Because there is a high prevalence of OSA in obese humans, it is possible that high MSNA reported in obese subjects may in fact reflect the presence of OSA in these subjects. We tested the hypothesis that obesity, per se, in th...

QUESTION A 4-year-old child was diagnosed by polysomnography as experiencing mild obstructive sleep apnea (OSA). Despite the child being inattentive and distracted during the day at school, his parents prefer to avoid surgical treatment (adenotonsillectomy). Are there any non-surgical treatments for mild OSA in young children? ANSWER Obstructive sleep apnea in children is caused mainly by ade...

Introduction: Obstructive sleep apnea (OSA) is common among adults worldwide and associated with an increased risk of both cardiac, metabolic, mental disease traffic accidents. However, evidence the different types upper airway surgery to relieve OSA symptoms sparse. Whether Drug induced sedation endoscopy (DISE) can improve outcome various surgical techniques in airways (UA) uncertain. The obj...