BACKGROUND Intracoronary physiology techniques have been validated extensively for the assessment of epicardial stenoses but not for the lone study of coronary microcirculation. We performed a comparison between 4 intracoronary physiological indices with the actual structural microcirculatory changes documented in transplanted hearts. METHODS AND RESULTS In 17 cardiac allograft patients witho...

The aim of this study is to evaluate the use of our nano-HA/PCL composite 3D scaffolds as graft materials for mastoid cavity obliteration in an animal model. Nano-HA particles were synthesized by chemical precipitation technique and mixed them with PCL solution to make composite paste. 3D scaffolds were fabricated by a paste extruding deposition process. The nano-HA/PCL 3D scaffolds showed good...

A remarkably high incidence of bronchiectasis and other pulmonary sequelae was observed in young children affected during an epidemic of severe lower respiratory tract infections apparently caused by adenovirus type 21. The histopathological findings are described in four cases in which one or both lungs were obtained for examination at intervals ranging from two months to three years after the...

Obliteration for gastric or duodenal variceal hemorrhage was performed via transileocoecal or transhepatic portal catheterization in 8 patients with portal hypertension. The patients were 6 men and 2 women, whose average age was 59 years. All of the patients had cirrhosis of the liver. The obliteration was performed as an emergency procedure in 6 cases, and 2 patients were electively treated. T...

OBJECTIVE To compare frontal sinus cranialization to obliteration for future prevention of secondary mucocele formation following open surgery for benign lesions of the frontal sinus. STUDY DESIGN Retrospective case series. SETTING Tertiary academic medical center. PATIENTS Sixty-nine patients operated for benign frontal sinus pathology between 1994 and 2011. INTERVENTIONS Open excision...

OBJECTIVE To describe the response to single dose photon stereotactic radiosurgery of arteriovenous malformations (AVMs) so that the probability of success or failure of treatment may be predicted for the individual patient. METHOD The obliteration prediction index (OPI) was calculated for AVMs by dividing the marginal dose of radiation in Gray (Gy) by the lesion diameter in centimetres in co...

AIM To describe our surgical technique and compare the results of obliteration materials. PATIENTS AND METHODS Fifty patients over a 7-year period were evaluated retrospectively. Out of these 50 consecutive patients, 29 had recurrent chronic otitis media (COM) with or without cholesteatoma and 21 patients had old open cavities. Efficacy of mastoid obliteration was assessed by an electronic ch...

The aim of the present study was to analyse which histological-histomorphometric findings correspond to a radiologically diagnosed open (group I) or closed mid-palatal suture (group II) on occlusal radiographs. For this purpose, 30 radiological regions of interest (rROI) from specimens obtained from 10 subjects ranging in age from 18 to 38 years were evaluated, and compared with the suture morp...

PURPOSE The objective of this study was to assess the value of high-resolution computed tomography (HRCT) and that of magnetic resonance imaging (MRI), including postcontrast T(1)-weighted images and echo-planar diffusion-weighted (EP-DW) images, in the detection of residual cholesteatomas after primary bony obliteration of the mastoid. PATIENTS AND METHODS Twenty-three patients underwent a s...

OBJECTIVE To assess middle ear aeration after total mastoid obliteration using bone pate and hydroxyapatite performed at the second stage of intact-canal-wall (ICW) tympanoplasty. STUDY DESIGN Retrospective study. SETTING Tertiary referral hospital. PATIENTS Forty-two ears with cholesteatoma underwent the obliteration. Computed tomography (CT) scan 1 week before the second-stage operation...