A virulent strain of Diaporthe gulyae, isolated from stem cankers of sunflower and known to be pathogenic to saffron thistle, has been shown to produce both known and previously undescribed metabolites when grown in either static liquid culture or a bioreactor. Together with phomentrioloxin, a phytotoxic geranylcyclohexenetriol recently isolated from a strain of Phomopsis sp., two new phytotoxi...

phorbiaceae. It is a shrub or small tree reaching 4—5 meters high and native to Thailand, where it is commonly called “Plao phae”. In this paper, we describe the isolation and structure elucidation of newly isolated 3 -(4 -hydroxy-3 ,5 dimethoxyphenyl)-propyl benzoate, 3 -(4 -hydroxyphenyl)propyl benzoate and four known compounds [3 -(4 -hydroxy-3 -methoxyphenyl)-propyl benzoate, poilaneic acid...

It has previously been proposed that 4-methylphenol (p-cresol) is metabolically activated by oxidation of the methyl group to form a reactive quinone methide. In the present study a new metabolism pathway is elucidated in human liver microsomes. Oxidation of the aromatic ring leads to formation of 4-methyl-ortho-hydroquinone, which is further oxidized to a reactive intermediate, 4-methyl-ortho-...

Three new complexes of Co(II), Ni(II), and Zn(II), containing ligand Schiff base (DHMA) derived from methyldopa (mdop) with 3-hydroxybenzaldehyde have been prepared. The synthesized its were diagnostics by using different physical techniques, results showed that the an octahedral shape. In addition it has studied adsorption behavior, Uv-Vis technique applied to survery isotherm adsorption. poss...

We have designed and synthesized novel bis-thiazole derivative. A 4-[bis(thiazol-2-ylamino)methyl]phenol was efficiently prepared in 71% yield by the reaction of 2-aminothiazole with 4-hydroxybenzaldehyde ethanol for 24 h. The structure newly obtained compound characterized 1H, 13C NMR mass spectrometry. Bis-thiazole derivative exhibits high tyrosinase inhibitory activity an IC50 value 29.71 μM...