نتایج جستجو برای: nutritional genomics
تعداد نتایج: 107537 فیلتر نتایج به سال:
Non-alcoholic fatty liver disease (NAFLD) is a rapidly emerging chronic liver disorder and will increasingly be a critical global health problem. Diet is an important pathogenic factor of NAFLD and it is well documented that the increased prevalence of NAFLD during the last decades was associated with deep modification of dietary habits, especially increased intakes of fats and simple carbohyd...
Phosphorus (P) is an essential nutrient for livestock but its efficiency of utilization is below 40%, contributing to environmental issues. In this review, we summarize recent approaches to optimize P availability in livestock diets and improve its utilization efficiency. Phase feeding could potentially reduce P excretion by 20%. Addition of phytase enzymes to diets increased P availability fro...
Genetics and genomics are certain to have a large impact in drug development and proper pharmaceutical treatment of subgroups of patients with many specific diseases. We should be able to increase the therapeutic margin for many agents. Genetic variation will also be important in refining estimates of risk from all kinds of environmental agents and in choosing more effective and more cost-effec...
Analysis of the increasing wealth of metagenomic data collected from diverse environments can lead to the discovery of novel branches on the tree of life. Here we analyse 5.2 Tb of metagenomic data collected globally to discover a novel bacterial phylum ('Candidatus Kryptonia') found exclusively in high-temperature pH-neutral geothermal springs. This lineage had remained hidden as a taxonomic '...
A functional genomics study revealed that the activity of acetyl-CoA synthetase 2 (ACSS2) contributes to cancer cell growth under low-oxygen and lipid-depleted conditions. Comparative metabolomics and lipidomics demonstrated that acetate is used as a nutritional source by cancer cells in an ACSS2-dependent manner, and supplied a significant fraction of the carbon within the fatty acid and phosp...
introduction: the mini nutritional assessment (mna) has been developed to assess malnutrition in elderly and to filter those who might get benefited from early diagnosis and treatment. the objective of the present study was to examine the nutritional profile of old age hospitalized individuals through the use of the mna in king khalid hospital at hail city of saudi arabia. methods: demographic...
General knowledge of the role of vitamin D3 in human physiology has been shaped by its discovery as a preventive agent of nutritional rickets, a defect in bone development due to inadequate uptake of dietary calcium. Studies on the function of the biologically active vitamin D3, 1,25-dihydroxyvitamin D3, have been greatly accelerated by the molecular cloning and structural analysis of the vitam...
Symbioses play an important role within the marine environment. Among the most well known of these symbioses is that between coral and the photosynthetic dinoflagellate, Symbiodinium spp. Understanding the metabolic relationships between the host and the symbiont is of the utmost importance in order to gain insight into how this symbiosis may be disrupted due to environmental stressors. Here we...
Fruit ripening is a sophisticatedly orchestrated developmental process, unique to plants, that results in major physiological and metabolic changes, ultimately leading to fruit decay and seed dispersal. Because of their strong impact on fruit nutritional and sensory qualities, the ripeningassociated changes have been a matter of sustained investigation aiming at unravelling the molecular and ge...
Hans-Georg Joost*, Michael J. Gibney, Kevin D. Cashman, Ulf Görman, John E. Hesketh, Michael Mueller, Ben van Ommen, Christine M. Williams and John C. Mathers German Institute of Human Nutrition Potsdam-Rehbruecke, Arthur-Scheunert-Allee 114-116, D-14558 Nuthetal, Germany IUNA Trinity College, Centre for Food and Health, St James’s Hospital, Dublin 8, Ireland IUNA University College Cork, Food ...
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