a series of 2-amino-4-aryl-3-cyano-7-(dimethylamino)-4 h -chromenes was synthesized by condensation of 3-(dimethylamino)phenol, an aromatic aldehyde and malonitrile in ethanol containing piperidine. the assignments of the structure of all synthesized compounds were based on spectral data (ir, mass and 1 h nmr). the cytotoxic activities of the synthesized compounds against six human tumor cell l...

background: little in known regarding the clinical relevance of sirt1 in multiple sclerosis (ms).   here, we aimed to evaluate mrna expression, protein level and enzyme activity of sirt1 in peripheral blood mononuclear cells (pbmcs) isolated from relapsing –remitting ms patients (rrms) and healthy controls. materials and methods: twenty patients with rr-ms and twenty two age- and sex-matched he...

background: although various surface disinfectants have been introduced, most of them are toxic. the use of natural antimicrobial agent e.g. phytol, extracted from leptadenia pyrotechnica is a new strategy. the aim of this study was to evaluate the antimicrobial activity, toxicity, and stability of phytol. methods: the serial concentrations of phytol were prepared, and separately incubated with...

the antimicrobial activity of methanolic extracts from different parts of 11 indigenous wild plantspecies used in traditional medicines of iran were tested against nine species of microorganisms: escherichiacoli, staphylococcus aureus, staphylococcus epidermis, pseudomonas aeruginosa, klebsiella pneumoniae,salmonella typhi, bacillus subtilis, aspergillus niger and candida albicans. the antimicr...

substituted schiff bases (hydrazones) 5a-j have been prepared from the starting material 2-chloro pyridine-3-carboxylic acid 1 by a sequence of reactions like reaction with 2-amino-6-nitro benzothiazole (ullamann condensation), thionyl chloride, hydrazine hydrate and different aromatic aldehydes. on cyclocondensation of 5a-j with thioglycolic acid in dry 1,4-dioxane furnished desired compounds ...

b a ckground: the present study aimed to demonstrate the seasonal activities of ixodes ricinus at the pasture level and on the host. m e t hods: a vast pasture in amol countryside (mazandaran province, iran) which had the potential for a considera- ble number of cattle and sheep to graze was chosen. tick sampling from the skin of 130 cattle and 130 sheep were collected every month interval. sim...

a series of n-substituted-2,4-thiazolidinedione derivatives (tzds) were prepared via n-alkylation of 2,4-tzd at position 3 using substituted benzyl halides. synthesized n-substituted-2,4-tzd was then substituted at position 5 with substituted aromatic aldehyde according to knoevenagel condensation method. structures of the compounds were elucidated using various spectral techniques viz. ir, 1hn...

background: educational interventions to promote physical activity are one of the health priorities. a theoretical approach to promote and maintain physical activity is the transtheoretical model (ttm). this research was conducted to determine the effects of this model on students' physical activity habits in 2011. methods: this quasi-experimental study was conducted on 200 students in two grou...

background: in this study, the inhibition rate of different oil concentrations containing pcbs (1242 and 1254 pcb arochlors) on the anaerobic biomass was investigated by specific methanogenic activity using the vials with volume of 120 ml. methods: original samples were divided into two groups: with soil containing pcbs and without pcbs and the control samples in both cases were just contained ...

objective: oxidative stress is involved in the pathophysiology of diabetes and cardiovascular complications of metabolic syndrome. the main objective of this study was to evaluate total antioxidant status by diphenylpicrylhydrazyl (dpph)-scavenging activity in patients developed metabolic syndrome (mets). materials and methods: forty-four patients with mets diagnosed on the basis of adult treat...