Membrane trafficking of the δ-opioid receptor (DOR) from intracellular compartments to plasma membrane in central neurons, induced by various pathological conditions such as long-term opioid exposure, represents unique receptor plasticity involved in the mechanisms of long-term opioid effects in opioid addiction and opioid treatment of chronic pain. However, the signaling pathways coupled to th...

Abstract Background Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is life-saving for severe hematological conditions. However, its outcomes need further improvement, and co-infusion of mesenchymal cells (MSCs) may show promise. A growing body research on this subject exists, while the results different trials are conflicting. systematic review meta-analysis needed to appraise r...

BACKGROUND Rapid immune reconstitution after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is significantly associated with lower infection, relapse and possibly secondary malignancy rates. The aim of this study was to investigate the role of peripheral lymphocyte subsets, especially CD3+CD8+ cytotoxic T cell recovery, in predicting transplant outcomes, including the overall su...

"Robustness", the network ability to maintain systematic performance in the face of intrinsic perturbations, and "response ability", the network ability to respond to external stimuli or transduce them to downstream regulators, are two important complementary system characteristics that must be considered when discussing biological system performance. However, at present, these features cannot ...

Urban revitalization has already become the main goal for urban managers. However, various stakeholders may have different perspectives on revitalization. Therefore, how managers understand stakeholders’ needs and determine sustainable development strategies a significant challenge. This study defines four driving aspects of (infrastructure construction, living environment, trade investment, co...

Purpose: This study aimed to observe and compare the efficacy of High-flow Nasal Cannula (HFNC) with/without a non-rebreather mask (NRM) on ICU-admitted COVID-19 diabetic patients.
 Methodology: We collected epidemiological, biochemical, clinical information from patients (diabetic = 136; non-diabetic 104) admitted into four hospitals in Chattogram, Bangladesh. SPSS v25 was used analyze da...

Abstract Bipartite networks that characterize complex relationships among data arise in various domains. The existing bipartite network models are mainly based on a type of relationship between objects, and cannot effectively describe multiple the real world. In this paper, we propose multi-relationship (MBN) model, which can two types realizes simple weighted reconstruction. Our model contains...

Chinese intangible cultural heritage is a treasure of culture and an important part human civilization, public participation our efforts to carefully guard pass on the historical lineage. This generation has relatively easy comfortable life due inter-generational relationships strong consumption power. Therefore, it crucial study values paths by which ICH products influence young people. paper ...