Melanoma (MSC) and non-melanoma skin cancer (NMSC) are the most common cancers in United States. Although NMSC accounts for greater proportion of diagnosed cases, MSC is more aggressive responsible over 80% cancer-related deaths. Adverse effects and/or resistance associated with existing treatment regimens have prompted new research efforts directed toward finding safer efficacious chemoprevent...

Human papillomaviruses (HPV) are increasingly recognised as important human carcinogens. The best established association with human malignancy is that of high-risk mucosal HPV types and anogenital cancer. HPV-induced transformation of anogenital epithelia has been the subject of intense research which has identified the cellular tumour suppressor gene products, p53 and pRB, as important target...

Skin cancer is one of the most common cancers. Melanoma accounts for less than 2% of skin cancer cases but causes a large majority of skin cancer deaths. Early detection of malignant melanoma remains the key factor in saving lives. However, the melanoma diagnosis is still clinically challenging. Here, we developed a confocal photothermal microscope for noninvasive, label-free, three-dimensional...

Human papillomaviruses (HPV) are increasingly recognised as important human carcinogens. The best established association with human malignancy is that of high-risk mucosal HPV types and anogenital cancer. HPV-induced transformation of anogenital epithelia has been the subject of intense research which has identified the cellular tumour suppressor gene products, p53 and pRB, as important target...

The number of melanocytic tumours has increased in the last decades, whereby the frequency of melanoma doubles every 20 years. At present there is a risk of 1:100 to falling sick with a melanoma. According to a WHO report, in the year 2006, about 48,000 melanoma related deaths occur worldwide per year (Lucas et al., 2006). The malignant melanoma is one of the less common types of skin cancer bu...

Skin is a vital component of the human body and covers the entire human system. Skin cancer is one of the complex and severe types of cancer. Nowadays young adults are mostly affected by skin cancer. In spite of the unforeseen progression medical science, curing skin cancer is a complex process. Malignant melanoma is one type of skin cancer, which cannot be cured and leads to death unless detec...