background many types of cardiovascular complications such as; cardiac arrhythmias, impaired cardiac function, myocardial ischemia and decreased left ventricular function, have been attributed to interferon therapy. objectives the aim of this study was to evaluate the effects of combination therapy pegylated interferon and ribavirin on left ventricular systolic and diastolic functions in patien...

Background: Cardiac markers in serum are measured in the early hours after the onset of symptoms not to detect Acute Myocardial Infarction (AMI) but to exclude MI. To rule out AMI, one frequently must rely on the measurement of cardiac enzymes or biochemical markers when patients suspected of AMI present with atypical chest pain or a non-diagnostic ECG. We studied the levels of troponin T, and ...

Patient history, physical examination, 12-lead electrocardiogram (ECG) and cardiac biomarkers are key components of an effective chest pain assessment. The first priority is excluding serious chest pain syndromes, namely acute coronary syndromes (ACSs), aortic dissection, pulmonary embolism, cardiac tamponade and tension pneumothorax. On history, the mnemonic SOCRATES (Site Onset Character Radi...

Previous studies suggest that serum myeloperoxidase (MPO) is a potentially useful biomarker to risk stratify troponin-negative patients with suspected myocardial ischemia. We hypothesized that the relationship between initial serum MPO levels would correlate with 30-day adverse cardiac outcomes for low risk emergency department (ED) patients with suspected myocardial ischemia. This prospective ...

Cardiovascular disease is a leading cause of death in the United Kingdom; however, most first presentations with chest pain to primary care have a non-cardiac cause. It is important to establish which patients’ symptoms are caused by obstructive coronary artery disease, so that these patients can be optimally managed to control angina and reduce mortality. To support clinical decision making, t...

55 patients, who admitted during three month to ccu ward of one academic hospital, participated in this study. 80% of these patients had delay to report of their chest pain and 4% of them had complete failure to report it. reasons for didn’t report of pain and its signs were unawareness of nurse and physician about problem that is occurring and unawareness of patient about need to saying this p...

STUDY OBJECTIVE Chest pain is the most common complaint among cocaine users who present to the emergency department (ED) seeking care, and many hospital resources are applied to stratify cocaine users in regard to future cardiac morbidity and mortality. Little is known about the longitudinal cardiac and noncardiac medical outcomes of cocaine users who have been stratified to an ED observation p...

OBJECTIVES This study was designed to determine the diagnostic value of adenosine cardiac magnetic resonance (CMR) in troponin-negative patients with chest pain. BACKGROUND We hypothesized that adenosine CMR could determine which troponin-negative patients with chest pain in an emergency department have coronary artery disease (CAD) or future adverse cardiac events. METHODS Adenosine stress...