نتایج جستجو برای: non alcoholic cirrhosis
تعداد نتایج: 1359109 فیلتر نتایج به سال:
Although alcohol abuse is the most common cause of liver cirrhosis in the United States, the enhancing effects of alcohol on the long-term prognosis of hepatitis C virus (HCV) related liver cirrhosis has not been clarified. To investigate how alcohol abuse influences the prognosis of hepatitis virus related liver cirrhosis, we studied 716 Japanese patients. Cumulative survival and hepatocellula...
OBJECTIVES In patients with cirrhosis, the hepatic venous pressure gradient (HVPG) is the reference method for the assessment of portal hypertension (PHT). Variceal pressure (VP) may be measured at endoscopy, but its relationship to the HVPG remains controversial. The aim of the study was to retrospectively compare HVPG and VP values obtained in a cohort of patients with cirrhosis and PHT. ME...
Abstract Background Little is known about the outcomes of liver cirrhosis patients with severe aortic stenosis (AS) who undergo transcatheter valve replacement (TAVR). Methods We undertook a retrospective analysis consecutive symptomatic AS underwent transfemoral-TAVR Sapien-3 at our Clinic between April 2015 and December 2018, yielding 32 on imaging including ultrasound and/or computed tomogra...
The prognoses of patients with alcoholic liver cirrhosis were compared between those who continued to drink and those who stopped. Clinical criteria were strictly set so as to control other variables affecting the prognoses. Four-year survival was significantly higher in the patients who stopped drinking than in those who continued to drink. Continued drinking worsens the prognosis of patients ...
Clinical features of 52 patients with alcoholic hepatic diseases were described. Of these patients 27 had alcoholic hepatic cirrhosis. As compared with hepatic cirrhosis due to icteric viral hepatitis, vascular spider, ascites and edema were found more frequently in alcoholic cirrhosis. Hepatic biopsy showed preponderance of cirrhotic changes of postnecrotic type. Twenty-five patients had alcoh...
BACKGROUND AND AIMS Blood lysosomal acid lipase (LAL) is reduced in non-alcoholic steatohepatitis, which is the major cause of cryptogenic cirrhosis (CC); few data on LAL activity in CC do exist. We investigated LAL activity in a cohort of patients with liver cirrhosis. METHODS This is a multicentre cohort study including 274 patients with liver cirrhosis of different aetiology from 19 centre...
Revised 28 April 2006 Accepted for publication 28 April 2006 . . . . . . . . . . . . . . . . . . . . . . . 1.0 INTRODUCTION Ascites is a major complication of cirrhosis, occurring in 50% of patients over 10 years of follow up. The development of ascites is an important landmark in the natural history of cirrhosis as it is associated with a 50% mortality over two years, and signifies the need to...
Chronic liver disease is known to cause several skin manifestations, including cutaneous vascular changes such as palmar erythema and spider angioma. Spider angioma has been reported to be associated with severe chronic liver disease [1]. A 54-year-old male patient presented herein had diagnosed alcoholic cirrhosis for ten years and upper gastrointestinal endoscopy revealed grade III esophageal...
Sulfotransferase (SULT) function has been well studied in healthy human subjects by quantifying mRNA and protein expression and determining enzyme activity with probe substrates. However, it is not well known if sulfotransferase activity changes in metabolic and liver disease, such as diabetes, steatosis, or cirrhosis. Sulfotransferases have significant roles in the regulation of hormones and e...
BACKGROUND We tested the hypothesis that observationally and genetically increased YKL-40 concentrations are associated with alcoholic liver and pancreas damage and disease. METHODS We performed cohort and mendelian randomization in 86,258 individuals from the Danish general population, with measured concentrations of plasma YKL-40 (n = 21 646) and CHI3L1 rs4950928 genotype (n = 84 738). RE...
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